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3,391 Result(s)
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Article
Open AccessHeat-related illness and dementia: a study integrating epidemiological and experimental evidence
Heat-related illness (HRI) is commonly considered an acute condition, and its potential long-term consequences are not well understood. We conducted a population-based cohort study and an animal experiment to ...
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The impact of photobiomodulation on sleep and life quality in hemodialysis patients: A randomized controlled trial
The quality of life (QoL) and sleep quality are closely linked to the physical and psychological health of end-stage renal disease (ESRD) patients, especially those underwent hemodialysis (HD) therapy. This st...
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Exploring the link between metformin use and adhesive capsulitis of the shoulder: a retrospective cohort study in Taiwan
The risk of adhesive capsulitis of shoulder in diabetic patients taking metformin has not been evaluated. We aimed for evaluating the relative risk of adhesive capsulitis of shoulder in diabetic patients takin...
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Early Therapeutic Drug Monitoring Optimizes Teicoplanin Use in Febrile Neutropenic Patients with Hematological Malignancies
A target trough concentration (Cmin) of teicoplanin ≥ 15–20 mg/L between the fourth and sixth day has been suggested for severe infections or management of febrile neutropenia (FN). Owing to no reports discussing...
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Efficiency of PGK1 proteins delivered to the brain via a liposomal system through intranasal route administration for the treatment of spinocerebellar ataxia type 3
A patient-friendly and efficient treatment method for patients with spinocerebellar ataxia type 3 (SCA3) was provided through a nose-to-brain liposomal system. Initially, PGK1 was overexpressed in HEK 293-84Q-...
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Open AccessDevelo** an entrustable professional activity for providing health education and consultation in occupational therapy and examining its validity
Entrustable Professional Activities (EPA)-based assessment is easily and intuitively used in evaluating the learning outcomes of competency-based medical education (CBME). This study aimed to develop an EPA fo...
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Open AccessPIKfyve, expressed by CD11c-positive cells, controls tumor immunity
Cancer treatment continues to shift from utilizing traditional therapies to targeted ones, such as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other myeloid cells with anti...
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Open AccessImproved prediction of anti-angiogenic peptides based on machine learning models and comprehensive features from peptide sequences
Angiogenesis is a key process for the proliferation and metastatic spread of cancer cells. Anti-angiogenic peptides (AAPs), with the capability of inhibiting angiogenesis, are promising candidates in cancer tr...
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Strategic legislation for the promotion of university–industry collaborations: a case study of Taiwan
The strategic utilization of technology to enhance industrial competitiveness and product quality is pivotal for economic growth. As universities own more inventions, collaborative efforts between industry and...
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Open AccessModeling First-Line Daratumumab Use for Newly Diagnosed, Transplant-Ineligible, Multiple Myeloma: A Cost-Effectiveness and Risk Analysis for Healthcare Payers
This study aimed to assess the cost-effectiveness of two regimens regarded as the standard of care for the treatment of newly diagnosed, transplant-ineligible multiple myeloma in Singapore: (1) daratumumab, le...
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Open AccessUse of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 Å
While cryogenic electron microscopy (cryo-EM) is fruitfully used for harvesting high-resolution structures of sizable macromolecules, its application to small or flexible proteins composed of small domains lik...
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Article
Can weekend catch-up sleep decrease the risk of cognitive dysfunction in older adults?
This study investigated whether weekend catch-up sleep was related to a decreased risk of cognitive dysfunction in older Taiwanese adults by using self-reported diaries and objective accelerometer measurements.
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Article
Open AccessHypotension prediction index for prevention of intraoperative hypotension in patients undergoing general anesthesia: a randomized controlled trial
Intraoperative hypotension is a common side effect of general anesthesia. Here we examined whether the Hypotension Prediction Index (HPI), a novel warning system, reduces the severity and duration of intraoper...
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Open AccessHigh prevalence of exon-13 variants in USH2A-related retinal dystrophies in Taiwanese population
Biallelic pathogenic variants in USH2A lead to Usher syndrome or non-syndromic retinitis pigmentosa, and shown to have geographical and ethnical distribution in previous studies. This study provided a deeper unde...
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Open AccessStudy on different isolation technology on the performance of blue micro-LEDs array applications
In this study, a 3 × 3 blue micro-LED array with a pixel size of 10 × 10 μm2 and a pitch of 15 μm was fabricated on an epilayer grown on a sapphire substrate using metalorganic chemical vapor deposition technolog...
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Article
Building Institutional Research Workforce in Postsecondary Education: Exploring Institutional Research Professionals’ Conceptualizations of their Professional Identities
To provide insights into how institutions can scaffold institutional researchers’ construction of strong professional identities, we employed a qualitative approach, rooted in the constructivist paradigm, whic...
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Article
Open AccessEmission characterizations and environmental impacts of off-road vehicles
This study measured particulate matter (PM) and gaseous pollutants in the exhaust of off-road vehicles (excavators, bulldozers) during idling and working. The fingerprint of metals in PM and the emission facto...
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Stereo digital image correlation (3D-DIC) for non-contact measurement and refinement of delta robot arm displacement and jerk
This study proposes using the stereo digital image correlation (3D-DIC) method to measure the delta robot arm displacement and jerk to verify the robot arm end-effector position and improve the absolute accura...
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Integrating online partial pair programming and socially shared metacognitive regulation for the improvement of students’ learning
Many universities around the world were forced to lock down and students had to continue their learning in online environments in response to the COVID-19 pandemic. Teachers thus had to adopt effective and app...
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Industry perspective on power electronics for electric vehicles
Driven by the global effort towards reduction of carbon dioxide emissions from cars, the gradual phase out of fuel cars accompanied by the rise of electric vehicles (EVs) has become a megatrend. Despite the ra...