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  1. Article

    Open Access

    N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry

    Oxidized cysteine residues are highly reactive and can form functional covalent conjugates, of which the allosteric redox switch formed by the lysine-cysteine NOS bridge is an example. Here, we report a noncan...

    Yung-Lin Wang, Chin-Yuan Chang, Ning-Shian Hsu, I-Wen Lo in Nature Communications (2023)

  2. Article

    Open Access

    Multiple Pleomorphic Tetramers of Thermostable Direct Hemolysin from Grimontia hollisae in Exerting Hemolysis and Membrane Binding

    Oligomerization of protein into specific quaternary structures plays important biological functions, including regulation of gene expression, enzymes activity, and cell–cell interactions. Here, we report the d...

    Yu-Kuo Wang, Sheng-Cih Huang, Chin-Yuan Chang, Wan-Ting Huang in Scientific Reports (2019)