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Structural basis for Lewis antigen synthesis by the α1,3-fucosyltransferase FUT9
Mammalian cell surface and secreted glycoproteins exhibit remarkable glycan structural diversity that contributes to numerous physiological and pathogenic interactions. Terminal glycan structures include Lewis...
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Article
Author Correction: Polymerization of the backbone of the pectic polysaccharide rhamnogalacturonan I
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Article
Polymerization of the backbone of the pectic polysaccharide rhamnogalacturonan I
Rhamnogalacturonan I (RG-I) is a major plant cell wall pectic polysaccharide defined by its repeating disaccharide backbone structure of [4)-α-d-GalA-(1,2)-α-l-Rha-(1,]. A family of RG-I:Rhamnosyltransferases (RR...
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Article
Open AccessNMR analysis suggests the terminal domains of Robo1 remain extended but are rigidified in the presence of heparan sulfate
Human roundabout 1 (hRobo1) is an extracellular receptor glycoprotein that plays important roles in angiogenesis, organ development, and tumor progression. Interaction between hRobo1 and heparan sulfate (HS) h...