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Article
Early combination treatment with baloxavir and peramivir for hospitalized adults with influenza A in Yokohama, Japan
Baloxavir marboxil is a new anti-influenza drug, but data on the clinical efficacy of a combination treatment of baloxavir and peramivir is scarce. We conducted a single-center retrospective analysis comparing...
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Article
A humanized MDCK cell line for the efficient isolation and propagation of human influenza viruses
Here, we developed hCK, a Madin-Darby canine kidney (MDCK) cell line that expresses high levels of human influenza virus receptors and low levels of avian virus receptors. hCK cells supported human A/H3N2 infl...
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Article
Open AccessDiversity of antigenic mutants of influenza A(H1N1)pdm09 virus escaped from human monoclonal antibodies
Since the 2017 Southern Hemisphere influenza season, the A(H1N1)pdm09-like virus recommended for use in the vaccine was changed because human, but not ferret, sera distinguish A(H1N1)pdm09 viruses isolated aft...
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Article
Open AccessReactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan
Seasonal influenza virus routinely causes epidemic infections throughout the world. Sporadic infections by H5N1, H5N6, and H7N9 viruses are also reported. To treat patients suffering from such viral infections...
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Article
Open AccessEvaluation of a new immunochromatographic assay for rapid identification of influenza A, B, and A(H1N1)2009 viruses
We evaluated Clearline Influenza A/B/(H1N1)2009, a new multi-line immunochromatographic assay for rapid detection of antigens of influenza A (Flu A), B (Flu B), and A(H1N1)2009 viruses. Clearline detected Flu ...
