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    Article

    Galectin-1 orchestrates an inflammatory tumor-stroma crosstalk in hepatoma by enhancing TNFR1 protein stability and signaling in carcinoma-associated fibroblasts

    Most cases of hepatocellular carcinoma (HCC) arise with the fibrotic microenvironment where hepatic stellate cells (HSCs) and carcinoma-associated fibroblasts (CAFs) are critical components in HCC progression....

    Yao-Tsung Tsai, Chih-Yi Li, Yen-Hua Huang, Te-Sheng Chang, Chung-Yen Lin in Oncogene (2022)

  2. Article

    Open Access

    PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity

    Obesity-related cardiovascular risk, end points, and mortality are strongly related to arterial stiffening. Current therapeutic approaches for arterial stiffening are not focused on direct targeting within the...

    Ju-Yi Chen, Yi-Pin Wu, Chih-Yi Li, Huei-Fen Jheng in Journal of Biomedical Science (2021)

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    Article

    Healthcare Utilization and Expenditures for Persons with Diabetes Comorbid with Mental Illnesses

    The aim of this study was to investigate healthcare utilization and expenditure for patients with diabetes comorbid with and without mental illnesses in Taiwan. People with diabetes comorbid with and without ...

    Chen-Hsiang Su, Herng-Chia Chiu, Hui-Min Hsieh, Ju-Yu Yen in Psychiatric Quarterly (2016)