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Article
Goji Ferment Ameliorated Acetaminophen-Induced Liver Injury in vitro and in vivo
This study aimed to investigate the hepatoprotective effects of lyophilized powder of goji ferment (LPGF) against acetaminophen (APAP)-induced hepatic damage in Hep3B cells and in mice. Eleven strains of lacti...
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Article
Monitoring of toxic heavy metals contamination in commonly used Chinese materia medica
Monitoring of toxic heavy metals (THMs) contamination, including lead (Pb), arsenic (As), cadmium (Cd), and mercury (Hg), for the quality control in Chinese materia medica (CMM) is critical for ensuring safe m...
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Article
The in vitro and in vivo anti-metastatic efficacy of oxythiamine and the possible mechanisms of action
This study examined the anti-metastatic effects of oxythiamine (OT) both in cell culture and in vivo. Cell culture results revealed that OT (0–20 μM) significantly inhibited the invasion and migration (IC50 = 8.7...
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Article
C/EBP beta and C/EBP delta expression is elevated in the early phase of ethanol-induced hepatosteatosis in mice
Alcohol, which is predominantly metabolized in the liver, is a major hepatic toxicant that readily induces hepatic steatosis. The expression of CCAAT enhancer binding protein (C/EBP), especially the C/EBP delt...