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Article
Open AccessPredictive approach for liberation from acute dialysis in ICU patients using interpretable machine learning
Renal recovery following dialysis-requiring acute kidney injury (AKI-D) is a vital clinical outcome in critical care, yet it remains an understudied area. This retrospective cohort study, conducted in a medica...
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Article
Open AccessAn automated ICU agitation monitoring system for video streaming using deep learning classification
To address the challenge of assessing sedation status in critically ill patients in the intensive care unit (ICU), we aimed to develop a non-contact automatic classifier of agitation using artificial intellige...
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Article
Open AccessProlonged use of neuromuscular blocking agents is associated with increased long-term mortality in mechanically ventilated medical ICU patients: a retrospective cohort study
Neuromuscular blockade agents (NMBAs) can be used to facilitate mechanical ventilation in critically ill patients. Accumulating evidence has shown that NMBAs may be associated with intensive care unit (ICU)-ac...
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Article
Open AccessFederated machine learning for predicting acute kidney injury in critically ill patients: a multicenter study in Taiwan
To address the contentious data sharing across hospitals, this study adopted a novel approach, federated learning (FL), to establish an aggregate model for acute kidney injury (AKI) prediction in critically il...
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Article
Open AccessAnaemia in the first week may be associated with long-term mortality among critically ill patients: propensity score-based analyses
Anaemia is highly prevalent in critically ill patients; however, the long-term effect on mortality remains unclear.
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Article
Open AccessExplainable machine learning approach to predict extubation in critically ill ventilated patients: a retrospective study in central Taiwan
Weaning from mechanical ventilation (MV) is an essential issue in critically ill patients, and we used an explainable machine learning (ML) approach to establish an extubation prediction model.
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Article
Open AccessExplainable machine learning to predict long-term mortality in critically ill ventilated patients: a retrospective study in central Taiwan
Machine learning (ML) model is increasingly used to predict short-term outcome in critically ill patients, but the study for long-term outcome is sparse. We used explainable ML approach to establish 30-day, 90...
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Article
Incidence and risk factors of mental illness among the spouses of patients with sepsis: a population-based cohort study
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Article
Open AccessCulture positivity may correlate with long-term mortality in critically ill patients
The long-term outcome is currently a crucial issue in critical care, and we aim to address the association between culture positivity and long-term mortality in critically ill patients.
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Article
Open AccessThe association between culture positivity and long-term mortality in critically ill surgical patients
The long-term outcome is an essential issue in critically ill patients, and the identification of early determinant is needed for risk stratification of the long-term outcome. In the present study, we investig...
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Article
Statistical Analysis on Heart Rate Variability for Graded Cardiopulmonary Groups with Different Exercise Intensities
Physical fitness indicates favorable statuses of well-being and health and, more specifically, the ability to perform sports and daily activities. In the paper, we studied heart rate variability with electroca...
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Article
Open AccessImpact of corticosteroid treatment on clinical outcomes of influenza-associated ARDS: a nationwide multicenter study
Corticosteroid treatment has been widely used in the treatment of septic shock, influenza, and ARDS, although some previous studies discourage its use in severe influenza patients. This multicenter retrospecti...
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Article
Open AccessHigher glycemic variability within the first day of ICU admission is associated with increased 30-day mortality in ICU patients with sepsis
High glycemic variability (GV) is common in critically ill patients; however, the prevalence and mortality association with early GV in patients with sepsis remains unclear.
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Article
Open AccessPredictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning
Patients with influenza complicated with pneumonia are at high risk of rapid progression to acute respiratory distress syndrome (ARDS). Prone positioning with longer duration and lung-protective strategies mig...
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Article
Open AccessUsing genoty** to delineate tuberculosis transmission in long-term care facilities: single facility 4-year experience
Residents in long-term care facilities (LTCFs) are vulnerable to tuberculosis (TB) transmission; however, to delineate possible routes of TB transmission in LTCFs is difficult. This study aimed to address the ...
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Article
Hypoxia can impair doxorubicin resistance of non-small cell lung cancer cells by inhibiting MRP1 and P-gp expression and boosting the chemosensitizing effects of MRP1 and P-gp blockers
Non-small cell lung cancers (NSCLCs) frequently exhibit resistance to therapeutic drugs, which seriously hampers their treatment. Here, we set out to assess the roles of the multidrug resistance protein 1 (MRP...
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Article
TGFβ can stimulate the p38/β-catenin/PPARγ signaling pathway to promote the EMT, invasion and migration of non-small cell lung cancer (H460 cells)
Signaling pathway(s) responsible for transforming growth factor β (TGFβ)-induced epithelial mesenchymal transition (EMT), invasion and migration of H460 cells (non-small cell lung cancer/NSCLC) was identified ...
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Article
Open AccessApplication and comparison of scoring indices to predict outcomes in patients with healthcare-associated pneumonia
Healthcare-associated pneumonia (HCAP) is a relatively new category of pneumonia. It refers to infections that occur prior to hospital admission in patients with specific risk factors following contact or expo...
