3 Result(s)
within
Chia-Ying Wu
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessThe phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling
DUSP22 is a dual-specificity phosphatase that inhibits T cell activation by inactivating the kinase Lck. Here we show that the E3 ubiquitin ligase UBR2 is a positive upstream regulator of Lck during T-cell act...
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Article
Open AccessAge-specific trend and birth cohort effect on different histologic types of uterine corpus cancers
To evaluate the uterine corpus cancer incidence rates, age-specific trends, and birth cohort patterns by different histologic types. We conducted a retrospective cohort study of uterine cancer patients (n = 28...
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Article
Open AccessRegulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β
Mutations in human CLC-1 chloride channel are associated with the skeletal muscle disorder myotonia congenita. The disease-causing mutant A531V manifests enhanced proteasomal degradation of CLC-1. We recently ...
