-
Article
Correction: Unraveling the Clinical Relevance of Ferroptosis-Related Genes in Human Ovarian Aging
-
Article
Cuproptosis-Related Gene FDX1 Identified as a Potential Target for Human Ovarian Aging
Cuproptosis is a recently discovered mode of cell death that has garnered attention due to its association with various diseases. However, the intricate genetic relationship between cuproptosis and ovarian agi...
-
Article
Open AccessSpatial and single-cell explorations uncover prognostic significance and immunological functions of mitochondrial calcium uniporter in breast cancer
The mitochondrial calcium uniporter (MCU) is a transmembrane protein facilitating the entry of calcium ions into mitochondria from the cell cytosol. Maintaining calcium balance is crucial for enhancing cellula...
-
Article
Open AccessSpatial and single-cell analyses uncover links between ALKBH1 and tumor-associated macrophages in gastric cancer
AlkB homolog 1, histone H2A dioxygenase (ALKBH1), a crucial enzyme involved in RNA demethylation in humans, plays a significant role in various cellular processes. While its role in tumor progression is well-e...
-
Article
Open AccessNew insight into the intravenous immunoglobulin treatment in Multisystem Inflammatory Syndrome in children and adults
Within 6 months of the coronavirus pandemic, a new disease entity associated with a multisystem hyperinflammation syndrome as a result of a previous infection with the SARS-CoV-2 virus is increasingly being id...
-
Article
Unraveling the Clinical Relevance of Ferroptosis-Related Genes in Human Ovarian Aging
Ferroptosis, a recently discovered form of cell death, has been implicated in various diseases. However, the genetic relationship between ferroptosis and ovarian aging has not been thoroughly investigated thro...
-
Article
Open AccessProgestin Primed Ovarian Stimulation (PPOS) protocol yields lower euploidy rate in older patients undergoing IVF
To explore if exogenous progestin required for progestin primed ovarian stimulation (PPOS) protocol compromises the euploidy rate of patients who underwent preimplantation genetic testing cycles when compared ...
-
Article
Elicitation of potent neutralizing antibodies in obese mice by ISA 51-adjuvanted SARS-CoV-2 spike RBD-Fc vaccine
Vaccination is considered to be the most effective countermeasure to prevent and combat the global health threats of COVID-19. People with obesity are at a greater risk of hospitalization, life-threatening ill...
-
Article
Open AccessAdditional single dose GnRH agonist during luteal phase support may improve live birth rate in GnRHa-HRT frozen–thawed embryo transfer cycle: a retrospective cohort study
GnRH agonist (GnRHa) has been reported to have direct effects and functional roles in the endometrium and embryos. Several meta-analyses have shown that GnRHa administration in the luteal phase improved the li...
-
Article
Open AccessArtificial oocyte activation may improve embryo quality in older patients with diminished ovarian reserve undergoing IVF-ICSI cycles
Artificial oocyte activation (AOA) is used to improve fertilization rate following fertilization failure after intracytoplasmic sperm injection (ICSI). Several studies have also shown that AOA may be involved ...
-
Article
Development and characterization of mouse monoclonal antibodies targeting to distinct epitopes of Zika virus envelope protein for specific detection of Zika virus
The recent Zika virus (ZIKV) epidemic poses a serious threat to global health due to its association with microcephaly and congenital diseases in newborns and neurological complications and Guillain-Barré synd...
-
Article
Development of mouse monoclonal antibody for detecting hemagglutinin of avian influenza A(H7N9) virus and preventing virus infection
Many cases of avian influenza A(H7N9) virus infection in humans have been reported since its first emergence in 2013. The disease is of concern because most patients have become severely ill with roughly 30% m...
-
Article
Open AccessSerum testosterone levels are positively associated with serum anti-mullerian hormone levels in infertile women
Anti-Mullerian hormone (AMH) and testosterone (T) both play distinct roles in the early stages of folliculogenesis. However, the relationship between serum T and AMH levels is poorly understood. This study aim...
-
Article
Hepatoma-derived growth factor participates in Helicobacter Pylori-induced neutrophils recruitment, gastritis and gastric carcinogenesis
Helicobacter pylori (Hp) infection and overexpression of hepatoma-derived growth factor (HDGF) are involved in gastric carcinogenesis. However, the relationship between Hp-induced gastric diseases and HDGF upregu...
-
Article
Synthesis of Ugi-4CR boronate analogues via microwave irradiation
The synthetic condition for the synthesis of boronate ester Ugi-4CR analogs under mild conditions was developed. The reported reactions were carried out in methanol and promoted by microwave heating. This synt...
-
Article
Open AccessSynergistic Protection of N-Acetylcysteine and Ascorbic Acid 2-Phosphate on Human Mesenchymal Stem cells Against Mitoptosis, Necroptosis and Apoptosis
Human mesenchymal stem cells (hMSCs) contribute to ischemic tissue repair, regeneration and possess ability to self-renew. However, poor viability of transplanted hMSCs within ischemic tissues has limited its ...