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Article
Open AccessImproving performance of deep learning models using 3.5D U-Net via majority voting for tooth segmentation on cone beam computed tomography
Deep learning allows automatic segmentation of teeth on cone beam computed tomography (CBCT). However, the segmentation performance of deep learning varies among different training strategies. Our aim was to p...
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Article
Open AccessPhiladelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukaemia (ALL), a high-risk subtype characterised by genomic alterations that activate cytokine receptor and kinase signalling, is associated with in...
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Article
Open AccessBAFF-driven NLRP3 inflammasome activation in B cells
BAFF supports B-cell survival and homeostasis by activating the NF-κB pathway. While NF-κB is also involved in the priming signal of NLRP3 inflammasome, the role of BAFF in NLRP3 inflammasome regulation is unk...
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Article
Open AccessFPGS relapse-specific mutations in relapsed childhood acute lymphoblastic leukemia
Although the cure rate for childhood acute lymphoblastic leukemia (ALL) has exceeded 80% with contemporary therapy, relapsed ALL remains a leading cause of cancer-related death in children. Relapse-specific mu...
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Article
Open AccessExploration and characterization of the memcapacitor and memristor properties of Ni–DNA nanowire devices
A 2-μm-long Ni ion-chelated DNA molecule (Ni–DNA) was found for the first time to possess both memcapacitor and memristor properties; this Ni–DNA molecule is known as a dual memory circuit element (memelement)...