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  1. No Access

    Article

    CuMoO4/Ti3C2Tx nanocomposite layers perform as an ultrasensitive electrochemical sensor for the detection of antioxidant rutin

    The focus of this paper is laid on synthesizing layered compounds of CuMoO4 and Ti3C2Tx using a simple wet chemical etching method and sonochemical method to enable rapid detection of rutin using an electrochemi...

    Jagadeesh Ramadoss, Mani Govindasamy, Arumugam Sonachalam in Microchimica Acta (2024)

  2. Article

    Open Access

    Medical students’ perceptions of integrating social media into a narrative medicine programme for 5th-year clerkship in Taiwan: a descriptive qualitative study

    The growing demands in integrating digital pedagogies in learning (e.g., social media) contribute to disrupting many fields, including the medical humanities education. However, the strengths and barriers behi...

    Yosika Septi Mauludina, Bao Lan Hoang, Tsai-Yu Wang in BMC Medical Education (2024)

  3. Article

    Open Access

    Is moderate resistance training adequate for older adults with sarcopenia? A systematic review and network meta-analysis of RCTs

    Resistance training (RT) and nutritional supplementation are recommended for the management of sarcopenia in older adults. However, optimal RT intensity for the treatment of sarcopenia has not been well invest...

    Yu Chang Chen, Wang-Chun Chen, Chia-Wei Liu in European Review of Aging and Physical Acti… (2023)

  4. Article

    Open Access

    Brain metastasis, EGFR mutation subtype and generation of EGFR-TKI jointly influence the treatment outcome of patient with EGFR-mutant NSCLC

    Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutation is brain metastasis (BM)-prone. We determined the impact of this hallmark, along with EGFR subtype and generation of tyrosi...

    Jia-Shiuan Ju, Allen Chung-Cheng Huang, Pi-Hung Tung, Chi-Hsien Huang in Scientific Reports (2023)

  5. Article

    A chemiresistive biosensor for detection of cancer biomarker in biological fluids using CVD-grown bilayer graphene

    A chemiresistive biosensor is described for simple and selective detection of miRNA-21. We developed chemical vapor deposition (CVD) and low-damage plasma treatment (LDPT)-treated bilayer graphene composite o...

    Mani Govindasamy, Chen-Rong Jian, Chang-Fu Kuo, Ao-Ho Hsieh in Microchimica Acta (2022)

  6. No Access

    Article

    Colloidal synthesis of perovskite-type lanthanum aluminate incorporated graphene oxide composites: Electrochemical detection of nitrite in meat extract and drinking water

    A novel electrochemical method has been developed for determination of nitrite using La-based perovskite-type lanthanum aluminate nanorod-incorporated graphene oxide nanosheets (LaAlO3@GO). Morphological and stru...

    Mani Govindasamy, Sea-Fue Wang, Chi-Hsien Huang, Razan A. Alshgari in Microchimica Acta (2022)

  7. Article

    Open Access

    The different overall survival between single-agent EGFR-TKI treatment and with bevacizumab in non-small cell lung cancer patients with brain metastasis

    Comparison of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) monotherapy or with bevacizumab in real-world non-small cell lung cancer (NSCLC) patients was lacking. 310 patients of advanc...

    Tzu-Hsuan Chiu, Pi-Hung Tung, Chi-Hsien Huang, Jia-Shiuan Ju in Scientific Reports (2022)

  8. Article

    Open Access

    The association of social frailty with intrinsic capacity in community-dwelling older adults: a prospective cohort study

    Social frailty is associated with poor health outcomes; however, its effects on healthy aging indicators have not been adequately investigated. This study assessed the longitudinal association between social f...

    Chi Hsien Huang, Kiwako Okada, Eiji Matsushita, Chiharu Uno in BMC Geriatrics (2021)

  9. No Access

    Article

    Dietary patterns and intrinsic capacity among community-dwelling older adults: a 3-year prospective cohort study

    The WHO has proposed a novel model of healthy aging called intrinsic capacity (IC). However, the association between dietary patterns and IC is unclear. We aimed to investigate the prospective associations bet...

    Chi Hsien Huang, Kiwako Okada, Eiji Matsushita in European Journal of Nutrition (2021)

  10. Article

    Open Access

    How does narrative medicine impact medical trainees’ learning of professionalism? A qualitative study

    Narrative medicine (NM) is an approach involving narrative skills and is regarded as a model for medical humanism and effective medical practice. This study aims to explore how NM impacts medical trainees’ lea...

    Chien-Da Huang, Chang-Chyi Jenq, Kuo-Chen Liao, Shu-Chung Lii in BMC Medical Education (2021)

  11. Article

    Open Access

    Mild hyponatremia is associated with low skeletal muscle mass, physical function impairment, and depressive mood in the elderly

    Mild hyponatremia (serum sodium 130–135 mEq/L) is a common electrolyte disorder in the elderly. However, its association with both sarcopenia and cognitive function remains to be clarified. Therefore, here we ...

    Chisato Fujisawa, Hiroyuki Umegaki, Taiki Sugimoto, Satoshi Samizo in BMC Geriatrics (2021)

  12. Article

    Open Access

    HOme-based Longitudinal Investigation of the multidiSciplinary Team Integrated Care (HOLISTIC): protocol of a prospective nationwide cohort study

    The use of home health care (HHC) is increasing worldwide. This may have an impact not only on patients and their caregivers’ health but on care resource utilization and costs. We lack information on the impac...

    Jung-Yu Liao, **-Jen Chen, Yu-Lin Wu, Ching-Hsia Cheng, Sang-Ju Yu in BMC Geriatrics (2020)

  13. No Access

    Article

    Prior EGFR-TKI Treatment in EGFR-Mutated NSCLC Affects the Allele Frequency Fraction of Acquired T790M and the Subsequent Efficacy of Osimertinib

    The first (1G) and second (2G) generations of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) show differential inhibitory capacities towards EGFR T790M-mutated non-small-cell lung cance...

    Chih-Hsi Scott Kuo, Chi-Hsien Huang, Chien-Ying Liu, Stelios Pavlidis in Targeted Oncology (2019)

  14. Article

    Open Access

    Predicting hospital-acquired pneumonia among schizophrenic patients: a machine learning approach

    Medications are frequently used for treating schizophrenia, however, anti-psychotic drug use is known to lead to cases of pneumonia. The purpose of our study is to build a model for predicting hospital-acquire...

    Kuang Ming Kuo, Paul C. Talley in BMC Medical Informatics and Decision Making (2019)

  15. Article

    Open Access

    Change in quality of life and potentially associated factors in patients receiving home-based primary care: a prospective cohort study

    The trajectories for health-related quality of life of patients receiving home-based primary care are not well identified. Our objective was to investigate changes in the quality of life (QOL) and factors that...

    Chi-Hsien Huang, Hiroyuki Umegaki, Hiroko Kamitani, Atushi Asai in BMC Geriatrics (2019)

  16. Article

    Open Access

    Continuance compliance of privacy policy of electronic medical records: the roles of both motivation and habit

    Hospitals have increasingly realized that wholesale adoption of electronic medical records (EMR) may introduce differential tangible/intangible benefits to them, including improved quality-of-care, reduced med...

    Kuang Ming Kuo, Yu Chang Chen in BMC Medical Informatics and Decision Making (2018)

  17. Article

    Open Access

    Is traumatic brain injury a risk factor for neurodegeneration? A meta-analysis of population-based studies

    To determine the association of prior traumatic brain injury (TBI) with subsequent diagnosis of neurodegeneration disease.

    Chi-Hsien Huang, Chi-Wei Lin, Yi-Che Lee, Chih-Yuan Huang, Ru-Yi Huang in BMC Neurology (2018)

  18. Article

    Open Access

    Fluorinated Graphene as High Performance Dielectric Materials and the Applications for Graphene Nanoelectronics

    There is broad interest in surface functionalization of 2D materials and its related applications. In this work, we present a novel graphene layer transistor fabricated by introducing fluorinated graphene (flu...

    Kuan-I Ho, Chi-Hsien Huang, Jia-Hong Liao, Wen**g Zhang in Scientific Reports (2014)

  19. Article

    Open Access

    Temperature dependence of time-resolved photoluminescence in closely packed alignment of Si nanodisks with SiC barriers

    We study the temperature dependence of time-resolved photoluminescence (PL) in closely packed alignment of Si nanodisks (NDs) with SiC barriers, fabricated by neutral beam etching using bio-nano-templates. The...

    Takayuki Kiba, Yoshiya Mizushima, Makoto Igarashi in Nanoscale Research Letters (2013)

  20. Article

    Open Access

    Immobilization of enzyme and antibody on ALD-HfO2-EIS structure by NH3 plasma treatment

    Thin hafnium oxide layers deposited by an atomic layer deposition system were investigated as the sensing membrane of the electrolyte-insulator-semiconductor structure. Moreover, a post-remote NH3 plasma treatmen...

    I-Shun Wang, Yi-Ting Lin, Chi-Hsien Huang, Tseng-Fu Lu in Nanoscale Research Letters (2012)

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