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Open AccessMaHPIC malaria systems biology data from Plasmodium cynomolgi sporozoite longitudinal infections in macaques
Plasmodium cynomolgi causes zoonotic malarial infections in Southeast Asia and this parasite species is important as a model for Plasmodium vivax and Plasmodium ovale. Each of these species produces hypnozoites i...
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Open AccessClinical recovery of Macaca fascicularis infected with Plasmodium knowlesi
Kra monkeys (Macaca fascicularis), a natural host of Plasmodium knowlesi, control parasitaemia caused by this parasite species and escape death without treatment. Knowledge of the disease progression and resilien...
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Article
Open AccessRobust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages
The ability to culture pathogenic organisms substantially enhances the quest for fundamental knowledge and the development of vaccines and drugs. Thus, the elaboration of a protocol for the in vitro cultivatio...
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Article
Open AccessAnalysis of erythrocyte dynamics in Rhesus macaque monkeys during infection with Plasmodium cynomolgi
Malaria is a major mosquito transmitted, blood-borne parasitic disease that afflicts humans. The disease causes anaemia and other clinical complications, which can lead to death. Plasmodium vivax is known for its...
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Article
Open AccessCorrection to: Integrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques
After publication of the article [1], it was brought to our attention that several symbols were missing from Fig. 1, including some cited in the figure’s key. The correct version of the figure is shown below and ...
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Article
Open AccessIntegrative analysis associates monocytes with insufficient erythropoiesis during acute Plasmodium cynomolgi malaria in rhesus macaques
Mild to severe anaemia is a common complication of malaria that is caused in part by insufficient erythropoiesis in the bone marrow. This study used systems biology to evaluate the transcriptional and alterati...
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Article
Open AccessA model of Plasmodium vivax concealment based on Plasmodium cynomolgi infections in Macaca mulatta
Plasmodium vivax can cause severe malaria. The total parasite biomass during infections is correlated with the severity of disease but not necessarily quantified accurately by microsco...
