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Article
Augmented BMP4 signal impairs tongue myogenesis
Tongue muscles are derived from mesodermal cells, while signals driven by cranial neural crest cells (CNCCs) regulate tongue myogenesis via tissue–tissue interaction. Based on such mechanisms of interaction, c...
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Article
Expression patterns of genes critical for SHH, BMP, and FGF pathways during the lumen formation of human salivary glands
Sjögren’s syndrome or radiotherapy for head and neck cancer leads to the irreversible hypofunction of salivary gland (SG). The stem/progenitor cell-based regenerative strategy has been proven to be the most pr...
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Article
Expression profile of critical genes involved in FGF signaling pathway in the develo** human primary dentition
Mammalian tooth development is regulated by paracrine signal molecules of several conserved family interactions between epithelium and mesenchyme. The expression patterns and regulative roles of FGF signaling ...
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Article
Genome-wide analysis of gene expression in human embryonic tooth germ
While numerous genes that play important regulatory roles during tooth development in mice have been identified, little is known about gene expression profile and their function during human odontogenesis. To ...
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Article
Precise chronology of differentiation of develo** human primary dentition
While correlation of developmental stage with embryonic age of the human primary dentition has been well documented, the available information regarding the differentiation timing of the primary teeth was larg...
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Article
Open AccessExpression of SHH signaling molecules in the develo** human primary dentition
Our current knowledge on tooth development derives primarily from studies in mice. Very little is known about gene expression and function during human odontogenesis. Sonic Hedgehog (SHH) signaling has been de...