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Article

Lactate-induced MRP1 expression contributes to metabolism-based etoposide resistance in non-small cell lung cancer cells

Metabolic reprogramming contributes significantly to tumor development and is tightly linked to drug resistance. The chemotherapeutic agent etoposide (VP-16) has been used clinically in the treatment of lung c...

Qi Dong, Chenkang Zhou, Haodong Ren, Zhijian Zhang… in Cell Communication and Signaling (2020)