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  1. No Access

    Article

    Schizophrenia in the genetic era: a review from development history, clinical features and genomic research approaches to insights of susceptibility genes

    Schizophrenia is a devastating neuropsychiatric disorder affecting 1% of the world population and ranks as one of the disorders providing the most severe burden for society. Schizophrenia etiology remains obsc...

    Ye Lv, Lin Wen, Wen-Juan Hu, Chong Deng, Hui-Wen Ren, Ya-Nan Bao… in Metabolic Brain Disease (2024)

  2. No Access

    Article

    PACAP/PAC1-R activation contributes to hyperalgesia in 6-OHDA-induced Parkinson’s disease model rats via promoting excitatory synaptic transmission of spinal dorsal horn neurons

    Pain is a common annoying non-motor symptom in Parkinson’s disease (PD) that causes distress to patients. Treatment for PD pain remains a big challenge, as its underlying mechanisms are elusive. Pituitary aden...

    Li-guo Dong, Meng-qi An, Han-ying Gu, Li-ge Zhang… in Acta Pharmacologica Sinica (2023)

  3. No Access

    Article

    Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson’s Disease

    Pain in Parkinson’s disease (PD) is increasingly recognized as a major factor associated with poor life quality of PD patients. However, classic therapeutic drugs supplying dopamine have limited therapeutic ef...

    Cheng-Jie Li, Li-Ge Zhang, Lu-Bing Liu, Meng-Qi An, Li-guo Dong… in Molecular Neurobiology (2022)

  4. No Access

    Article

    Tension–Compression Asymmetry Improved by Cold Extrusion in Pure Magnesium

    In this paper, cold extrusion was successfully used to fabricate the fine-grained pure Mg bar with average grain size of 2.5 μm. The microstructure, texture and mechanical properties were evaluated by electron...

    Cheng-jie Li, Shuang Cheng, Hong-fei Sun… in Journal of Materials Engineering and Perfo… (2018)