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Chapter
Structural Insights into Regulation of Vibrio Virulence Gene Networks
One of the best studied aspects of pathogenic Vibrios are the virulence cascades that lead to the production of virulence factors and, ultimately, clinical outcomes. In this chapter, we will examine the regula...
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Article
Open AccessStructure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons
Enteric infections caused by the gram-negative bacteria enterotoxigenic Escherichia coli (ETEC), Vibrio cholerae, Shigella flexneri, and Salmonella enterica are among the most common and affect billions of people...
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Article
Open AccessPublisher Correction: A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessA disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
ToxR is a transmembrane transcription factor that, together with its integral membrane periplasmic binding partner ToxS, is conserved across the Vibrionaceae family. In some pathogenic Vibrios, including V. parah...