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    Chapter

    Structural Insights into Regulation of Vibrio Virulence Gene Networks

    One of the best studied aspects of pathogenic Vibrios are the virulence cascades that lead to the production of virulence factors and, ultimately, clinical outcomes. In this chapter, we will examine the regula...

    Charles R. Midgett, F. Jon Kull in Vibrio spp. Infections (2023)

  2. Article

    Open Access

    Structure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons

    Enteric infections caused by the gram-negative bacteria enterotoxigenic Escherichia coli (ETEC), Vibrio cholerae, Shigella flexneri, and Salmonella enterica are among the most common and affect billions of people...

    Charles R. Midgett, Kacey Marie Talbot, Jessica L. Day in Scientific Reports (2021)

  3. Article

    Open Access

    Publisher Correction: A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Charles R. Midgett, Rachel A. Swindell, Maria Pellegrini, F. Jon Kull in Scientific Reports (2020)

  4. Article

    Open Access

    A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts

    ToxR is a transmembrane transcription factor that, together with its integral membrane periplasmic binding partner ToxS, is conserved across the Vibrionaceae family. In some pathogenic Vibrios, including V. parah...

    Charles R. Midgett, Rachel A. Swindell, Maria Pellegrini, F. Jon Kull in Scientific Reports (2020)