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ASO Visual Abstract: The Predictive Utility of MammaPrint and BluePrint in Identifying Patients with Locally Advanced Breast Cancer Who are Most Likely to have Nodal Downstaging and a Pathologic Complete Response After Neoadjuvant Chemotherapy
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Article
Open AccessThe Predictive Utility of MammaPrint and BluePrint in Identifying Patients with Locally Advanced Breast Cancer Who are Most Likely to Have Nodal Downstaging and a Pathologic Complete Response After Neoadjuvant Chemotherapy
Neoadjuvant chemotherapy (NCT) increases the feasibility of surgical resection by downstaging large primary breast tumors and nodal involvement, which may result in surgical de-escalation and improved outcomes...
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Article
A Prospective, Single Arm, Multi-site, Clinical Evaluation of a Nonradioactive Surgical Guidance Technology for the Location of Nonpalpable Breast Lesions during Excision
This study was a multicenter evaluation of the SAVI SCOUT® breast localization and surgical guidance system using micro-impulse radar technology for the removal of nonpalpable breast lesions. The study was design...
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Article
Pilot Study of a New Nonradioactive Surgical Guidance Technology for Locating Nonpalpable Breast Lesions
The current technique for locating nonpalpable breast lesions is wire localization (WL). Radioactive seed localization and intraoperative ultrasound were developed to improve difficulties with WL. The SAVI SC...
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Article
Clinical Outcomes of Breast-Conserving Surgery in Patients Using a Modified Method for Cavity Margin Assessment
This study describes a modified intraoperative method for cavity margin (CM) assessment in place of lumpectomy margin assessment in patients undergoing breast-conserving surgery (BCS).
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Article
Axillary Recurrence Rate Following Negative Sentinel Node Biopsy for Invasive Breast Cancer: Long-Term Follow-Up
Sentinel lymph node (SLN) biopsy has replaced axillary lymph node dissection (ALND) as the definitive nodal staging procedure for breast cancer. SLN biopsy has been proven to cause less morbidity and be more c...
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Article
Consequences of Axillary Ultrasound in Patients with T2 or Greater Invasive Breast Cancers
Axillary ultrasound (AUS) with needle biopsy is used to detect metastasis in patients with invasive breast cancers. Our hypothesis is that preoperative AUS significantly reduces sentinel node biopsy (SLNB) use...
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Article
Erratum to: Axillary Recurrence Rate Following Negative Sentinel Node Biopsy for Invasive Breast Cancer: Long-Term Follow-Up
Sentinel lymph node (SLN) biopsy has replaced axillary lymph node dissection (ALND) as the staging procedure for breast cancer. SLN biopsy causes less morbidity and is more cost effective than complete ALND. L...
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Article
Open AccessIntramammary Sentinel Lymph Nodes: What is the Clinical Significance?
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Chapter
Frozen Section and Imprint Cytology in Sentinel Lymph Node Biopsy for Breast Cancer
Recent trends toward conservative surgery for breast cancer and increasing detection of smaller invasive malignancies have shifted the traditional surgical approach from mastectomy to lumpectomy, and from comp...
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Chapter
Sentinel Lymph Node Biopsy in Patients with Breast Cancer
The term “sentinel node” was first used by Gould et al. in 1960 to describe the first node in the drainage pathway of a malignant tumor (1). In 1977, Cabanas proposed that sentinel lymph nodes could be removed an...
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Article
Sentinel Node Biopsy Before Neoadjuvant Chemotherapy for Determining Axillary Status and Treatment Prognosis in Locally Advanced Breast Cancer
Treatment of locally advanced breast cancer with neoadjuvant chemotherapy assesses an in vivo tumor response while increasing breast conservation. Axillary clearance of nodal disease after treatment defines pr...
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Article
Surgical Complications Associated With Sentinel Lymph Node Biopsy: Results From a Prospective International Cooperative Group Trial
American College of Surgeons Oncology Group Z0010 is a prospective multicenter trial designed to evaluate the prognostic significance of micrometastases in the sentinel lymph nodes and bone marrow aspirates of...
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Article
Novel techniques in sentinel lymph node map** and localization of nonpalpable breast lesions: The moffit experience
The concept of lymphatic map** has helped to redefine the clinical significance of lymph nodes with respect to breast cancer. The combination technique using both blue dye and radiocolloid is the most effect...
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Article
Radioactive Seed Localization Breast Biopsy and Lumpectomy: Can Specimen Radiographs Be Eliminated?
Background: Wire localization (WL) is the current standard for surgical diagnosis of nonpalpable breast lesions. Many disadvantages inherent to WL are solved with radioactive seed localiz...
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Article
Utility of Internal Mammary Lymph Node Removal When Noted by Intraoperative Gamma Probe Detection
Background: Lymphatic map** LM for breast cancer has made internal mammary node IMN detection practical and dependable. This study demonstrates the necessity of IMN removal when suggested by intraoperative radi...
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Randomized Prospective Evaluation of a Novel Technique for Biopsy or Lumpectomy of Nonpalpable Breast Lesions: Radioactive Seed Versus Wire Localization
Background: Standard wire localization (WL) and excision of nonpalpable breast lesions has several shortcomings.
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Article
Sentinel Node Biopsy in Ductal Carcinoma In Situ Patients
Background: Sentinel lymph node (SLN) map** is an effective and accurate method of evaluating the regional lymph nodes in breast cancer patients. The SLN is the first node that receives lymphatic drainage from ...
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Article
Implementation of New Surgical Technology: Outcome Measures for Lymphatic Map** of Breast Carcinoma
Background: Recent advances in technology and the subsequent development of minimally invasive surgical techniques have heralded a new era in the surgical treatment of breast cancer. The dilemma of how to train s...
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Article
Microstaging of Breast Cancer Patients Using Cytokeratin Staining of the Sentinel Lymph Node
Background: Sentinel lymph node (SLN) map** is an effective and accurate method of axillary nodal evaluation for metastatic disease. Cytokeratin (CK) immunohistochemical (IHC) staining of the SLN has found micr...