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Article
Intra-individual Dose Escalation of Abiraterone According to Its Plasma Exposure in Patients with Progressive Metastatic Castration-Resistant Prostate Cancer: Results of the OPTIMABI Trial
Trough abiraterone concentration (ABI Cmin) of 8.4 ng/mL has been identified as an appropriate efficacy threshold in patients treated for metastatic castration-resistant prostate cancer (mCRPC). The aim of the ph...
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Article
External validation and comparison of magnetic resonance imaging-based risk prediction models for prostate biopsy stratification
Magnetic resonance imaging (MRI) is a promising tool for risk assessment, potentially reducing the burden of unnecessary prostate biopsies. Risk prediction models that incorporate MRI data have gained attentio...
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Article
The impact of prostate volume estimation on the risk‐adapted biopsy decision based on prostate-specific antigen density and magnetic resonance imaging score
Utility of prostate-specific antigen density (PSAd) for risk-stratification to avoid unnecessary biopsy remains unclear due to the lack of standardization of prostate volume estimation. We evaluated the impact...
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Article
Open versus robotic partial nephrectomy in obese patients: a multi-institutional propensity score-matched analysis (UroCCR 43—Robese study)
There is limited evidence on the outcomes of robotic partial nephrectomy (RPN) and open partial nephrectomy (OPN) in obese patients (BMI ≥ 30 kg/m2). In this study, we aimed to compare perioperative and oncologic...
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Article
Contrast enhancement early after renal malignancy cryoablation: imaging findings associated with benignity
Contrast enhancement by MRI done early after cryoablation for renal malignancies may suggest residual tumor (RT). However, we have observed MRI enhancement within 48 h of cryoablation in patients who had no co...
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Article
What is the ideal combination therapy in de novo, oligometastatic, castration-sensitive prostate cancer?
To review current evidence regarding the management of de novo, oligometastatic, castration-sensitive prostate cancer (PCa).
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Article
Expanding inclusion criteria for active surveillance in intermediate-risk prostate cancer: a machine learning approach
To develop new selection criteria for active surveillance (AS) in intermediate-risk (IR) prostate cancer (PCa) patients.
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Article
Open AccessActive surveillance in renal transplant patients with prostate cancer: a multicentre analysis
Due to medical improvements leading to increased life expectancy after renal transplantation and widened eligibility criteria allowing older patients to be transplanted, incidence of (low-risk) prostate cancer...
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Article
Micro-ultrasound-guided biopsies versus systematic biopsies in the detection of prostate cancer: a systematic review and meta-analysis
The diagnosis of prostate cancer (PCa) still relies on the performance of both targeted (TB) and systematic biopsies (SB). Micro-ultrasound (mUS)-guided biopsies demonstrated a high sensitivity in detecting cl...
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Article
Heterogeneity of contemporary grade group 4 prostate cancer in radical prostatectomy specimens
The aim was to evaluate the prognostic role of sub-categories of ISUP 4 prostate cancer (PCa) on final pathology, and assess the tumor architecture prognostic role for predicting biochemical recurrence (BCR) a...
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Article
Grade group 1 prostate cancer on biopsy: are we still missing aggressive disease in the era of image-directed therapy?
Recently, Eggener et al. reignited a debate consisting to redefine Gleason Grade Group (GGG) 1 prostate cancer (PCa) as a precancerous lesion to reduce overdiagnosis and overtreatment. However, historical cohorts...
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Article
Prostate luminal progenitor cells: from mouse to human, from health to disease
Stem and progenitor cells of the adult prostate epithelium have historically been believed to reside mainly or exclusively within the basal cell compartment and to possess basal-like phenotypic characteristics...
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Article
Annual nationwide analysis of costs and post-operative outcomes after radical prostatectomy according to the surgical approach (open, laparoscopic, and robotic)
Annual countrywide data are scarce when comparing surgical approaches in terms of hospital stay outcomes and costs for radical prostatectomy (RP). We aimed to assess the impact of surgical approach on post-ope...
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Article
Validation of the new STAR-CAP prognostic group staging system in prostate cancer patients treated with radiation therapy
To externally validate the STAR-CAP prognostic system for prostate cancer (PCa) and compare it to the CAPRA score to predict for biochemical recurrence (BCR) after radiation therapy (RTx).
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Article
Delayed retroperitoneal liposarcoma diagnosis and management in a patient with massive obesity
People suffering from extreme obesity may be exposed to delayed diagnosis and treatment of cancer. A 37-year-old woman (weight = 245 kg, body mass index (BMI) = 79 kg/m2), presented a sepsis associated with nonsp...
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Article
Open AccessPostoperative outcomes of elderly patients undergoing partial nephrectomy
To describe clinical outcomes of patients aged 75 years and above after partial nephrectomy (PN), and to assess independent factors of postoperative complications. We retrospectively reviewed information from ...
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Article
Observation vs. early drainage for grade IV blunt renal trauma: a multicenter study
The aim of this study was to compare observation and early drainage by ureteral stenting in patients with blunt renal trauma and urinary extravasation.
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Article
Advanced ultrasound in the diagnosis of prostate cancer
The diagnosis of prostate cancer (PCa) can be challenging due to the limited performance of current diagnostic tests, including PSA, digital rectal examination and transrectal conventional US. Multiparametric ...
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Article
Persistent orchialgia after laparoscopic living-donor nephrectomy: an underestimated complication requiring information adjustment
Laparoscopic living-donor nephrectomy (LLDN) is the gold-standard procedure for kidney procurement. Ipsilateral orchialgia has barely been described. Some authors reported that ligation of gonadal vein (GV) ab...
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Article
Prostatic Artery Embolization Allows to Maintain Full Sexual Activity in Patients Suffering from Bothersome Lower Urinary Tracts Symptoms related to Benign Prostatic Hyperplasia
The effect of prostate artery embolization (PAE) on male sexual function is currently the subject of debate in the literature. The main purpose of this study was to define changes in all domains of sexual acti...
