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    Article

    High Rates of Ultraviolet-Signature Mutations in Squamous Cell Carcinomas of the Parotid Gland and Prognostic Implications

    In the absence of clear pathologic differences, clinical history may differentiate potential primary parotid squamous cell carcinomas (SCC) from metastases. The presence of an ultraviolet (UV) signature can di...

    Shira Fishbach, George Steinhardt, Chao Jie Zhen, Rutika Puranik… in Head and Neck Pathology (2022)

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    Article

    Clinical Validation and Implementation of a Measurable Residual Disease Assay for NPM1 in Acute Myeloid Leukemia by Error-Corrected Next-Generation Sequencing

    Nucleophosmin 1 (NPM1) is one of the most commonly mutated genes in acute myeloid leukemia, with mutations observed in approximately 30% of all adult cases. The persistence of NPM1 mutations following chemotherap...

    Lauren L. Ritterhouse, Megan Parilla, Chao Jie Zhen… in Molecular Diagnosis & Therapy (2019)