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Article
Open AccessStroke–heart syndrome: current progress and future outlook
Stroke can lead to cardiac complications such as arrhythmia, myocardial injury, and cardiac dysfunction, collectively termed stroke–heart syndrome (SHS). These cardiac alterations typically peak within 72 h of...
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Article
Direct Ischemic Postconditioning Following Stroke Thrombectomy: A Promising Therapy for Reperfusion Injury
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Article
Open AccessCombination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke
Prognosis is critically important in stroke cases, with angiogenesis playing a key role in determining outcomes. This study aimed to investigate the potential protective effects of Atractylenolide I (Atr I), A...
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Article
Open AccessRemote ischemic conditioning reduces adverse events in patients with acute ischemic stroke complicating acute myocardial infarction: a randomized controlled trial
Acute ischemic stroke (AIS) complicating an acute myocardial infarction (AMI) is not uncommon, but can severely worsen the clinical prognosis. This study aimed to investigate whether remote ischemic conditioni...
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Article
Open AccessEvaluation of peripapillary retinal nerve fiber layer thickness in intracranial atherosclerotic stenosis
To evaluate the peripapillary retinal nerve fiber layer thickness (pRNFL) in patients with intracranial atherosclerotic stenosis (ICAS).
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Article
Risk and risk factor of ischemic stroke after acute retinal arterial ischemia
We aimed to confirm the risk and risk factor for ischemic stroke after acute retinal arterial ischemia (ARAI).
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Article
Open AccessCalpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury
Studies have shown that transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) protects against brain damage. However, the low survival number of transplanted BMSCs remains a pertinent challenge...
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Chapter
Ischemic Stroke Pathophysiology and Cell Therapy
Current evidence shows great promise for stem cell transplantation as a new therapeutic strategy for stroke. However, stem cell transplantation for stroke is still in its infancy, with many issues that need to...
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Article
Open AccessAssessment of Serum UCH-L1 and GFAP in Acute Stroke Patients
A rapid and reliable diagnostic test to distinguish ischemic from hemorrhagic stroke in patients presenting with stroke-like symptoms is essential to optimize management and triage for thrombolytic therapy. Th...
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Protocol
Animal Stroke Model: Ischemia–Reperfusion and Intracerebral Hemorrhage
Stroke is a major health issue worldwide—one with serious financial and public health implications. As a result, ongoing clinical research on novel and improved stroke therapies is not only pertinent but also ...
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Article
Nanotheragnostic Applications for Ischemic and Hemorrhagic Strokes: Improved Delivery for a Better Prognosis
Stroke is the second leading cause of death worldwide and a major cause of long-term severe disability representing a global health burden and one of the highly researched medical conditions. Nanostructured ma...
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Open AccessReliability analysis of the Ahringer Caenorhabditis elegans RNAi feeding library: a guide for genome-wide screens
The Ahringer C. elegans RNAi feeding library prepared by cloning genomic DNA fragments has been widely used in genome-wide analysis of gene function. However, the library has not been thoroughly validated by dire...
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Article
Sodium sulfite is a potential hypoxia inducer that mimics hypoxic stress in Caenorhabditis elegans
Physical and chemical hypoxia have been widely used in the study of hypoxic injury; however, both of these hypoxia models have their own limitations. Physical hypoxia is usually difficult to control and mainta...
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Article
Open AccessA proteomic view of Caenorhabditis elegans caused by short-term hypoxic stress
The nematode Caenorhabditis elegans is both sensitive and tolerant to hypoxic stress, particularly when the evolutionarily conserved hypoxia response pathway HIF-1/EGL-9/VHL is involved. Hypoxia-induced changes i...
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Article
A novel method for promoting heterologous protein expression in Escherichia coli by fusion with the HIV-1 TAT core domain
The human immunodeficiency virus type 1 (HIV-1) transactivator of transcription (TAT) protein, a member of the protein transduction domain (PTD) superfamily, can deliver heterologous proteins across most biome...
