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Article

PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407

Colorectal cancer (CRC) is the third most common cause of cancer deaths, and has a high rate of liver and lung metastasis. Unfortunately, distant metastasis is the main barrier for advanced CRC therapy and lea...

**n Tan, Shuai Chen, Jiangxue Wu, Jiaxin Lin, Changchuan Pan… in Cell Death & Disease (2017)