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  1. Article

    Open Access

    PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407

    Colorectal cancer (CRC) is the third most common cause of cancer deaths, and has a high rate of liver and lung metastasis. Unfortunately, distant metastasis is the main barrier for advanced CRC therapy and lea...

    **n Tan, Shuai Chen, Jiangxue Wu, Jiaxin Lin, Changchuan Pan… in Cell Death & Disease (2017)

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  2. Article

    Open Access

    OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

    OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a deubiquitinating enzyme (DUB) that belongs to the OTU (ovarian tumor) superfamily. The aim of this study was to clarify the role of OTUB1 in colore...

    Yi Zhou, Jiangxue Wu, **ang Fu, Wuying Du, Ling Zhou, **angqi Meng… in Molecular Cancer (2014)

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  3. No Access

    Article

    Subdividing the M1 stage of liver metastasis for nasopharyngeal carcinoma to better predict metastatic survival

    In nasopharyngeal carcinoma (NPC), the M1 stage of the TNM classification does not differentiate between the site of metastasis or the number of metastatic lesions. However, NPC patients with lung or bone meta...

    Changchuan Pan, Ni He, Ming Zhao, Yangkui Gu, Zilin Huang, Wang Li… in Medical Oncology (2011)