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Article
Atromentin and Leucomelone, the First Inhibitors Specific to Enoyl-ACP Reductase (FabK) of Streptococcus pneumoniae
Two potent inhibitors of FabK, the enoyl-acyl carrier protein (ACP) reductase of Streptococcus pneumoniae, were isolated from the solid state fermentation of an unidentified fungus F010248. Their structures were ...
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Article
Verticillin G, a New Antibacterial Compound from Bionectra byssicola
A new epidithiodioxopiperazine compound named verticillin G along with the known compound verticillin D has been isolated from the mycelium of liquid fermentation cultures of a fungal strain Bionectra byssicola F...
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Article
Viridicatumtoxin B, a new anti-MRSA agent from Penicillium sp. FR11
A new tetracycline-type antibiotic named viridicatumtoxin B along with the known compound viridicatumtoxin has been isolated from the mycelium of liquid fermentation cultures of Penicillium sp. FR11. The structur...
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Article
Macrolactin S, a New Antibacterial Agent with Fab G-inhibitory Activity from Bacillus sp. AT28
In the course of screening for FabG inhibitors from microbial sources, a new 24-membered ring lactone named macrolactin S, along with the known compound macrolactin B, has been isolated from the mycelium of li...
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Article
Isodeoxyhelicobasidin, a novel human neutrophil elastase inhibitor from the culture broth of Volvariella bombycina
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Article
Synthesis and potential antibacterial activity of new rhodanine-3-acetic acid derivatives
A series of rhodanine-3-acetic acid derivatives were synthesized and investigated for their antibacterial activity against gram-positive bacteria including multidrug-resistant clinical isolates. Among these co...
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Article
Synthesis and antibacterial evaluation of furan derivatives bearing a rhodanine moiety
Two series of furan derivatives bearing a rhodanine moiety (4a–l and 5a–l) have been synthesized, characterized, and evaluated for their antibacterial activity. The majority of these compounds showed potent level...
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Article
Novel arylhydrazone derivatives bearing a rhodanine moiety: synthesis and evaluation of their antibacterial activities
A series of arylhydrazone derivatives bearing a rhodanine moiety have been synthesized, characterized, and evaluated as antibacterial agents. Some of these compounds showed potent antibacterial activities agai...
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Article
Synthesis and biological evaluation of ursolic acid derivatives containing an aminoguanidine moiety
Three series of ursolic acid derivatives containing an aminoguanidine moiety were designed, synthesized, and evaluated for anti-bacterial and anti-inflammatory activity. Some compounds displayed potent anti-ba...
