Skip to main content

3 Result(s)

within Chang-Hai Fu Remove this filter

and

  1. No Access

    Article

    miR-132 Regulates PTSD-like Behaviors in Rats Following Single-Prolonged Stress Through Fragile X-Related Protein 1

    Fragile X-related protein 1 (FXR1) is a member of the fragile X family of RNA-binding proteins, which regulates a number of neurological and neuropsychiatric disorders such as fragile X syndrome, and is expect...

    Peng-Yin Nie, Li-Li Ji, Chang-Hai Fu, Jun-Bo Peng… in Cellular and Molecular Neurobiology (2021)

  2. Article

    Open Access

    miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein

    FMRP is a selective mRNA-binding protein that regulates protein synthesis at synapses, and its loss may lead to the impairment of trace fear memory. Previously, we found that FMRP levels in the hippocampus of ...

    Peng-Yin Nie, Lei Tong, Ming-Da Li, Chang-Hai Fu… in Journal of Neuroinflammation (2021)

    Download PDF (9122 KB) View Article

  3. Article

    Open Access

    Intra-hippocampal administration of ZIP alleviates depressive and anxiety-like responses in an animal model of posttraumatic stress disorder

    Given that impairment of fear extinction has been implicated in the pathogenesis of posttraumatic stress disorder (PTSD), effective pharmacological interventions that facilitate fear extinction may provide alt...

    Li-Li Ji, Lei Tong, Bao-Ku Xu, Chang-Hai Fu, Wan Shu… in Behavioral and Brain Functions (2014)

    Download PDF (652 KB) View Article