2,484 Result(s)
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Chang** Li
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Article
Open AccessPCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging
Bone marrow adipocytes (BMAds) affect bone homeostasis, but the mechanism remains unclear. Here, we showed that exercise inhibited PCNA clamp-associated factor (PCLAF) secretion from the bone marrow macrophage...
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Open AccessCorrelates of oral pre-exposure prophylaxis cessation among men who have sex with men in China: implications from a nationally quantitative and qualitative study
Several studies have demonstrated the population-level effectiveness of oral PrEP in reducing the risk of HIV infection. However, oral PrEP utilization among MSM in China remains below 1%. While existing liter...
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Author Correction: PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
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Research on Optimization Method of Home Energy Management System in Smart Grid
In order to save users' electricity costs, this paper proposes an optimized management method for the home energy management system. Firstly, a household power grid is constructed that include photovoltaic sys...
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Research on Energy Optimization Method of Multi-microgrid System Based on the Cooperative Game Theory
Aiming at the energy optimization problem of multi-microgrid system, a energy optimization method of multi-microgrid system is proposed based on cooperative game theory in this paper. Firstly, taking economic ...
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Study of Turbulent Behavior and Particle Flight Characteristics Based on Different Turbulence Models During HVOF Spraying
High-velocity oxygen fuel (HVOF) thermal spraying technology has been widely used to prepare anti-corrosion and wear-resistant coatings. In this study, the compressible turbulent flow, combustion reaction, and...
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PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
Synchronized ferroptosis contributes to nephron loss in acute kidney injury (AKI). However, the propagation signals and the underlying mechanisms of the synchronized ferroptosis for renal tubular injury remain...
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Nonlinear vibration analysis in high speed milling of single crystal silicon considering dynamic cutting thickness
In the milling process, the spindle vibration response is an important factor affecting the machining quality and accuracy. In this article, the mechanism of cutting vibration coupling is analyzed, and the dyn...
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Urate-lowering agents do not have clinically relevant negative effects on sperm quality and reproductive hormones in men with gout: a prospective open-label cohort study
The objective of this study was to analyze and compare the effects of different urate-lowering agents on testicular functions in men with gout in a clinical setting.
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Open AccessActivation of the osteoblastic HIF-1α pathway partially alleviates the symptoms of STZ-induced type 1 diabetes mellitus via RegIIIγ
The hypoxia-inducible factor-1α (HIF-1α) pathway coordinates skeletal bone homeostasis and endocrine functions. Activation of the HIF-1α pathway increases glucose uptake by osteoblasts, which reduces blood glu...
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Numerical simulation of multi-field coupling behavior and heat and mass transfer mechanism in laser additive manufacturing process
The serviceability of cladding layers manufactured by laser depends on the microstructure formed by the metallurgical solidification. The microstructure in the clad layer is influenced by several factors. Amon...
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Effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice
Exercise can induce beneficial improvements in cognition. However, the effects of different modes and intensities of exercise have yet to be explored in detail. This study aimed to identify the effects of diff...
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Open AccessImpaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study
Glucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) with nuclear sequestration at low plasma glucose level. Some GK activators (GKAs) disrupt ...
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Genetic susceptibility to breast cancer increases the risk of neutropenia and agranulocytosis: insights from Mendelian randomization
The causal relationship between breast cancer and its estrogen receptor (ER) subtypes and neutropenia and agranulocytosis is unclear.
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Open AccessUnraveling active sites regulation and temperature-dependent thermodynamic mechanism in photothermocatalytic CO2 conversion with H2O
In the photothermal synergistic catalytic conversion of CO2 and H2O, the catalyst harnesses solar energy to accumulate heat, thereby elevating the reaction system’s temperature. The influence of this temperature ...
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Open AccessHeparin Therapy and Mortality in Patients with Sepsis: An Observational Study Using a Marginal Structural Cox Model Based on MIMIC-IV Database
Although heparin has been widely used in clinical practice, its effect on mortality in sepsis is still controversial. This study aimed to investigate the effectiveness of heparin in septic patients.
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Parallel degradome-seq and DMS-MaPseq substantially revise the miRNA biogenesis atlas in Arabidopsis
MicroRNAs (miRNAs) are produced from highly structured primary transcripts (pri-miRNAs) and regulate numerous biological processes in eukaryotes. Due to the extreme heterogeneity of these structures, the initi...
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Pesticide application behavior in green tea cultivation and risk assessment of tea products: a case study of Rizhao green tea
Previous research on pesticides in green tea mainly focused on detection technology but lacked insights into pesticide use during cultivation. To address this gap, a survey was conducted among Rizhao green tea...
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Sensitivity analysis of the process parameters of the composite process of submerged arc surfacing and laser cladding
In steel industry, the descaling rolls is subject to the long-term high-pressure water erosion, dynamic impact, strong wear, and high temperature, which is prone to wear and corrosion failure affecting the con...
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Involvement of energy and cell wall metabolisms in chilling tolerance improved by hydrogen sulfide in cold-stored tomato fruits
Hydrogen sulfide improved cold resistance of tomato fruits by regulating energy metabolism and delaying cell wall degradation, thereby alleviating the damage of cold storage on fruits.
