-
Article
Open AccessModulation of synaptic transmission through O-GlcNAcylation
O-GlcNAcylation is a posttranslational modification where N-acetylglucosamine (O-GlcNAc) is attached and detached from a serine/threonine position by two enzymes: O-GlcNAc transferase and O-GlcNAcase. In addit...
-
Article
Open AccessNanoparticle Exsolution on Perovskite Oxides: Insights into Mechanism, Characteristics and Novel Strategies
Fundamental mechanisms in terms of driving force, material design, and exsolution processes are outlined, and novel behaviors of socketing and shape-shifting throughout the int...
-
Article
Open AccessNULISA: a proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing
The blood proteome holds great promise for precision medicine but poses substantial challenges due to the low abundance of most plasma proteins and the vast dynamic range of the plasma proteome. Here we addres...
-
Article
Metal-free, visible light-mediated atom transfer radical polymerization of hydroxypropyl cellulose-graft-poly(methyl methacrylate)s: effect of polymer side chains on thermo-responsive behavior of hydroxypropyl cellulose
We exploited organic photo-redox-catalyzed atom transfer radical polymerization (O-ATRP) to synthesize a thermo-responsive polymer with a narrow molecular weight distribution. Poly(methyl methacrylate) (PMMA) ...
-
Article
Open AccessTrajectory of bolt and length of plate in femoral neck system determine the stability of femur neck fracture and risk of subsequent subtrochanteric fracture : a finite element analysis
This study aimed to analyze the differences in the stability of fractures, stress distribution around the distal-most screw according to the length of the plate and the trajectory of the bolt in Pauwels type I...
-
Article
BES1-Mediated Brassinosteroid Signaling Negatively Regulates Biosynthesis and Signaling of Abscisic Acid to Increase Seed Size in Arabidopsis
Expression of ABA-deficient 2 (ABA2) gene involved in ABA biosynthesis was downregulated in bes1-D, but upregulated in bes1-KO. Hence, the expression of ABA2 is negatively controlled by the BES1 transcription fac...
-
Article
Usefulness and Molecular Mechanism of Seed-Specificity Introduced by AtBZR1 and AtBES1 to Improve Seed Yield and Quality in Arabidopsis thaliana
This study generated the transgenic Arabidopsis lines pAt5g54000-AtBZR1::Col-0 and pAt5g54000-AtBES1::Col-0, in which Arabidopsis BZR1 and BES1 (AtBZR1 and AtBES1) were seed-specifically expressed with pAt5g54000
-
Article
Various congenital anomalies and anatomical variations of the spleen: a multimodality pictorial review
There are various congenital anomalies and anatomical variations of the spleen (CAAVS). CAAVS are common and are often associated with systemic anomalies. Widespread use of computed tomography and magnetic res...
-
Article
Brassinosteroids and Salicylic Acid Mutually Enhance Endogenous Content and Signaling to Show a Synergistic Effect on Pathogen Resistance in Arabidopsis thaliana
The crosstalk mechanism regulating content and signal transduction between brassinosteroids (BRs) and salicylic acid (SA) for plant defense was investigated in Arabidopsis. Compared to the wild type, an increased...
-
Article
Gadoxetate disodium-enhanced MRI for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: late portal venous phase may improve identification of enhancing capsule
To investigate added value of late portal venous phase (LPVP) for identification of enhancing capsule (EC) on gadoxetate disodium-enhanced MRI (GD-MRI) for diagnosing hepatocellular carcinoma (HCC) in patients...
-
Chapter
Intraoperative Messung der Anteversion eines zementfreien Schaftes
Die Anteversion des Femurschaftes ist zu einem Problem geworden, da retrovertierte oder übermäßig antevertierte Schäfte zu einem Im**ement und einer Dislokation nach einer Hüfttotalendoprothese (HTEP) führen...
-
Article
Open AccessArtificial intelligence and machine learning on diagnosis and classification of hip fracture: systematic review
In the emergency room, clinicians spend a lot of time and are exposed to mental stress. In addition, fracture classification is important for determining the surgical method and restoring the patient's mobilit...
-
Article
Deconvoluting signals downstream of growth and immune receptor kinases by phosphocodes of the BSU1 family phosphatases
Hundreds of leucine-rich repeat receptor kinases (LRR-RKs) have evolved to control diverse processes of growth, development and immunity in plants, but the mechanisms that link LRR-RKs to distinct cellular res...
-
Article
Seed-Specifically Overexpressed Arabidopsis Cytochrome P450 85A2 Promotes Vegetative and Reproductive Growth and Development of Arabidopsis thaliana
Arabidopsis Cytochrome P450 85A2 (AtCYP85A2) was introduced to Arabidopsis thaliana seeds using a seed-specific promoter, pAt5g54000. GUS (β-Glucuronidase) activity and RT-PCR analysis demonstrated that AtCYP85A2
-
Article
Open AccessImproved control over implant anchorage under the use of the femoral neck system for fixation of femoral neck fractures: a technical note
The depth of bolt in Femoral neck system (FNS, DePuy Synthes, Oberdorf, Switzerland) is difficult to finely control as the length of the bolt is in units of 5 mm. Thus, this study introduces a method to contro...
-
Article
A spatiotemporal molecular switch governs plant asymmetric cell division
Asymmetric cell division (ACD) requires protein polarization in the mother cell to produce daughter cells with distinct identities (cell-fate asymmetry). Here, we define a previously undocumented mechanism for...
-
Chapter
Intraoperative Measurement of Cementless Stem Anteversion
Anteversion of the femoral stem has become a matter of concern because retroverted or excessively anteverted stems might lead to an im**ement and dislocation after total hip arthroplasty (THA). When using a ...
-
Article
Open AccessThe impact of sequential therapy from short-term teriparatide to denosumab compared with denosumab alone in patients with osteoporotic hip fracture: a 1-year follow-up study
Sequential therapy from bone-forming medication to resorptive agents is reportedly effective for patients with severe osteoporosis. The objective of this study is to determine the impact of implementing short-...
-
Article
Open AccessA CRISPR/dCas9 toolkit for functional analysis of maize genes
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system has become a powerful tool for functional genomics in plants. The RNA-guided nuclease can be used to not only generate precise ge...
-
Article
Gadoxetic acid-enhanced MRI for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: can hypointensity on the late portal venous phase be used as an alternative to washout?
To investigate the added value of considering hypointensity on late portal venous phase (LPVP) images as washout for diagnosis of hepatocellular carcinoma (HCC) using gadoxetic acid-enhanced MRI (Gd-EOB-MRI) i...
