Skip to main content

3 Result(s)

within Catherine C. Hogan Remove this filter

and

  1. No Access

    Article

    Duplicate Gene Evolution Toward Multiple Fates at the Drosophila melanogaster HIP/HIP-Replacement Locus

    Hsc/Hsp70-interacting protein (HIP) is a rapidly evolving Hsp70 cofactor. Analyses of multiple Drosophila species indicate that the HIP gene is duplicated only in D. melanogaster. The HIP region, in fact, contain...

    Catherine C. Hogan, Brian R. Bettencourt in Journal of Molecular Evolution (2009)

  2. Article

    Open Access

    Inducible and constitutive heat shock gene expression responds to modification of Hsp70 copy number in Drosophila melanogaster but does not compensate for loss of thermotolerance in Hsp70null flies

    The heat shock protein Hsp70 promotes inducible thermotolerance in nearly every organism examined to date. Hsp70 interacts with a network of other stress-response proteins, and dissecting the relative roles of...

    Brian R Bettencourt, Catherine C Hogan, Mario Nimali, Brian W Drohan in BMC Biology (2008)

    Download PDF (761 KB) View Article

  3. No Access

    Article

    Polyglutamine expansion in Drosophila: thermal stress and Hsp70 as selective agents

    Repetitive DNA sequences that encode polyglutamine tracts are prone to expansion and cause highly deleterious phenotypes of neurodegeneration. Despite this tendency, polyglutamine tracts (“polyQs”) are conserv...

    Brian R Bettencourt, Catherine C Hogan, Mario Nimali in Journal of Biosciences (2007)