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Article
Open AccessEnvironmental impact of the diet of young Portuguese and its relationship with adherence to the Mediterranean Diet
To estimate, in a cohort of young Portuguese adults, the environmental impact (greenhouse gas (GHG) emissions, land use, energy used, acidification and potential eutrophication) of diet according to adherence ...
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Chapter and Conference Paper
Analysis on Noncompact Manifolds and Index Theory: Fredholm Conditions and Pseudodifferential Operators
We provide Fredholm conditions for compatible differential operators on certain Lie manifolds (that is, on certain possibly non-compact manifolds with nice ends). We discuss in more detail the case of manifold...
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Article
Open AccessAssessing clinical applicability of COVID-19 detection in chest radiography with deep learning
The coronavirus disease 2019 (COVID-19) pandemic has impacted healthcare systems across the world. Chest radiography (CXR) can be used as a complementary method for diagnosing/following COVID-19 patients. Howe...
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Article
Neurological manifestations of adult-onset Still’s disease—case-based review
Adult-onset Still’s disease (AOSD) is a rare inflammatory disorder in which pathophysiology is yet to be fully understood. We report the case of a 66-year-old male that presents with fever, arthralgia, and lab...
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Article
Assessment of Poor Inhaler Technique in Older Patients with Asthma or COPD: A Predictive Tool for Clinical Risk and Inhaler Performance
Older patients with asthma or chronic obstructive pulmonary disease (COPD) are particularly susceptible to inhaler technique errors and poor clinical outcomes. Several factors may influence their risk, but mos...
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Chapter and Conference Paper
A Multi-dataset Approach for DME Risk Detection in Eye Fundus Images
Diabetic macular edema is a leading cause of visual loss for patients with diabetes. While diagnosis can only be performed by optical coherence tomography, diabetic macular edema risk assessment is often perfo...
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Article
Metastasis is impaired by endothelial-specific Dll4 loss-of-function through inhibition of epithelial-to-mesenchymal transition and reduction of cancer stem cells and circulating tumor cells
Systemic inhibition of Dll4 has been shown to thoroughly reduce cancer metastasis. The exact cause of this effect and whether it is endothelial mediated remains to be clarified. Therefore, we proposed to analy...
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Chapter and Conference Paper
Deep Learning Approaches for Gynaecological Ultrasound Image Segmentation: A Radio-Frequency vs B-mode Comparison
Ovarian cancer is one of the pathologies with t...
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Chapter
Fredholm Conditions on Non-compact Manifolds: Theory and Examples
We give explicit Fredholm conditions for classes of pseudodifferential operators on suitable singular and non-compact spaces. In particular, we include a “user’s guide” to Fredholm conditions on particular cla...
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Article
Cortical bone analysis in a predialysis population: a comparison with a dialysis population
This study was designed to characterize cortical bone by histomorphometry in a predialysis population, to correlate turnover, mineralization, and volume between cortical and trabecular bone, and to compare the...
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Article
Open AccessMethylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance
Microvascular dysfunction has been suggested to trigger adipose tissue dysfunction in obesity. This study investigates the hypothesis that glycation impairs microvascular architecture and expandability with an...
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Article
The role of bone biopsy for the diagnosis of renal osteodystrophy: a short overview and future perspectives
Chronic kidney disease (CKD) patients present specific bone and mineral metabolism disturbances, which account for important morbidity and mortality. The term renal osteodystrophy, classically used for the nom...
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Article
An Index Formula for Perturbed Dirac Operators on Lie Manifolds
We prove an index formula for a class of Dirac operators coupled with unbounded potentials, also called “Callias-type operators”. More precisely, we study operators of the form
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Chapter and Conference Paper
Classification Approach for Measurement of Atherosclerosis Using B-Mode Ultrasound Carotid Images
This paper presents an approach for the detection and delineation of the interfaces at the near and far walls of carotid artery using B-mode ultrasound images. After the delineation the system measures automat...
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Article
Layer potentials C*-algebras of domains with conical points
To a domain with conical points Ω, we associate a natural C*-algebra that is motivated by the study of boundary value problems on Ω, especially using the method of layer potentials. In two dimensions, we allow Ω ...
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Article
Regularity for Eigenfunctions of Schrödinger Operators
We prove a regularity result in weighted Sobolev (or Babuška–Kondratiev) spaces for the eigenfunctions of certain Schrödinger-type operators. Our results apply, in particular, to a non-relativistic Schrödinger...
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Article
Advanced Technologies for Oral Controlled Release: Cyclodextrins for Oral Controlled Release
Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion complexes formation, with the following advantages for the drugs: (1) solubility, dissolution rate, stability, and bioava...
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Chapter and Conference Paper
On Maltsev Digraphs
We study digraphs preserved by a Maltsev operation, Maltsev digraphs. We show that these digraphs retract either onto a directed path or to the disjoint union of directed cycles, showing that the constraint sa...
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Article
Open AccessHaemolytic anaemia secondary to arsenic poisoning: a case report
We report the case of a 56-year-old white man who presented at the Emergency Department for evaluation of dark-red urine. Rapid development of acute renal failure and haemolytic anaemia initially elicited the ...
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Article
CD(4) has bounded width
We prove that the constraint languages invariant under a short sequence of Jónsson terms (containing at most three non-trivial ternary terms) are tractable by showing that they have bounded width. This improve...