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  1. Article

    Open Access

    Recovery of muscular tissue and functional results of patients treated with a gluteus maximus flap transfer due to chronic abductor deficiency after total hip arthroplasty

    To evaluate the function of the abductor mechanism after a gluteus maximus flap transfer due to a degeneration of the muscles after hip arthroplasty, we analyzed the post-operative functional outcome as well a...

    Paul Ruckenstuhl, Georgi Wassilew in Archives of Orthopaedic and Trauma Surgery (2024)

  2. Article

    Open Access

    An interpretable data-driven prediction model to anticipate scoliosis in spinal muscular atrophy in the era of (gene-) therapies

    5q-spinal muscular atrophy (SMA) is a neuromuscular disorder (NMD) that has become one of the first 5% treatable rare diseases. The efficacy of new SMA therapies is creating a dynamic SMA patient landscape, wh...

    Tu-Lan Vu-Han, Rodrigo Bermudez Schettino, Claudia Weiß in Scientific Reports (2024)

  3. Article

    Open Access

    Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow

    Bone marrow plasma cells (BMPC) are the correlate of humoral immunity, consistently releasing antibodies into the bloodstream. It remains unclear if BMPC reflect different activation environments or maturation...

    Marta Ferreira-Gomes, Yidan Chen, Pawel Durek in Nature Communications (2024)

  4. Article

    Open Access

    Periacetabular osteotomy for symptomatic hip dysplasia in middle aged patients: does age alone matter?

    Conflicting evidence exists regarding outcomes in middle-aged patients undergoing periacetabular osteotomy (PAO) for symptomatic developmental dysplasia of the hip (DDH).

    Vincent J. Leopold, Christian Hipfl in Archives of Orthopaedic and Trauma Surgery (2024)

  5. No Access

    Living Reference Work Entry In depth

    Komplikationen der Hüftendoprothetik: Gefäßverletzungen

    Gefäßverletzungen gehören zu den seltenen, aber schwerwiegenden Komplikationen in der Endoprothetik. Bereits präoperativ ist jeder Eingriff auf das Vorliegen von Risikofaktoren für eine Gefäßverletzung zu prüf...

    Stefanie Donner, Carsten Perka in AE-Manual der Endoprothetik

  6. Article

    Open Access

    Bilateral simultaneous knee arthroplasty shows comparable early outcome and complication rate as staged bilateral knee arthroplasty for patients scored ASA 1–3 if performed by a high-volume surgeon: a retrospective cohort study of 127 cases

    The study compares early outcomes after simultaneous and staged knee arthroplasty in patients with bilateral knee osteoarthritis (OA) to evaluate whether simultaneous bilateral TKA shows comparable early outco...

    Stephanie Kirschbaum, Robert Hube in Archives of Orthopaedic and Trauma Surgery (2024)

  7. Article

    Open Access

    Bilateral simultaneous hip arthroplasty shows comparable early outcome and complication rate as staged bilateral hip arthroplasty for patients scored ASA 1-3 if performed by a high-volume surgeon

    The aim of this study was to compare early outcomes after simultaneous and staged hip arthroplasty (THA) in patients with bilateral symptomatic pathology.

    Stephanie Kirschbaum, Robert Hube, Carsten Perka in International Orthopaedics (2023)

  8. Article

    Open Access

    Two-stage revision for periprosthetic joint infection in cemented total hip arthroplasty: an increased risk for failure?

    The impact of the prior fixation mode on the treatment outcome of chronic periprosthetic joint infection (PJI) of the hip is unclear. Removal of cemented total hip arthroplasty (THA) is particularly challengin...

    Christian Hipfl, Vincent Leopold, Luis Becker in Archives of Orthopaedic and Trauma Surgery (2023)

  9. Article

    Open Access

    The influence of lumbo-sacral transitional vertebrae in developmental dysplasia of the hip: a matched pair analysis

    Lumbo-sacral transitional vertebrae (LSTV) are the most common congenital alteration of the lumbo-sacral junction and known to significantly influence pelvic anatomy. However, the influence of LSTV on dysplasi...

    Luis Becker, Christian Hipfl, Friederike Schömig, Carsten Perka in Scientific Reports (2023)

  10. Article

    Open Access

    Is a preoperative pathogen detection a prerequisite before undergoing one-stage exchange for prosthetic joint infection of the hip?

    A preoperative pathogen detection is considered a prerequisite before undergoing one-stage exchange for prosthetic joint infection (PJI) according to most guidelines. This study compares patients with and with...

    Daniel Karczewski, Yannick Seutz in Archives of Orthopaedic and Trauma Surgery (2023)

  11. Article

    Open Access

    Functional gait analysis reveals insufficient hindfoot compensation for varus and valgus osteoarthritis of the knee

    The hindfoot is believed to compensate varus and valgus deformities of the knee by eversion and inversion movements. But these mechanisms were merely found in static radiologic measurements. The aim of this st...

    Marlene Rühling, Stephanie Kirschbaum, Carsten Perka in International Orthopaedics (2023)

  12. Article

    Open Access

    Two-stage exchange for PJI with co-existing cerclages for fracture: higher rates of early re-infections and difficult to treat microbes

    Periprosthetic joint infections (PJI) with osteosynthesis material for contemporaneous fractures are a challenging, yet poorly described condition. This study will analyze PJI with co-existing fractures treate...

    Daniel Karczewski, Maximilian Müllner in Archives of Orthopaedic and Trauma Surgery (2023)

  13. Article

    Open Access

    The role of biopsy in diagnosing infection after hip and knee arthroplasty: a meta-analysis

    Early diagnosis of periprosthetic hip and knee infection still represents a major challenge, as no single test can achieve ideal results. Currently, multiple preoperative indicators were performed to diagnose ...

    Cheng Li, Donara Margaryan, Carsten Perka in Archives of Orthopaedic and Trauma Surgery (2023)

  14. No Access

    Article

    Fixationstechniken bei periazetabulärer Osteotomie

    Die periazetabuläre Osteotomie nach Ganz (PAO) ist eine etablierte Technik zur operativen Therapie der Hüftgelenksdysplasie mit dem Ziel, das dysplastische Hüftgelenk biomechanisch zu optimieren. Durch die meh...

    Vincent Justus Leopold, Carsten Perka, Sebastian Hardt in Die Orthopädie (2023)

  15. Article

    Open Access

    Cure rate of infections is not an argument for spacer in two-stage revision arthroplasty of the hip

     A devastating complication after total hip arthroplasty (THA) is chronic periprosthetic joint infection (PJI). Most frequently spacers (Sp) with or without antibiotics are implanted in a two-stage procedure e...

    Dominik Adl Amini, Chia H. Wu, Carsten Perka in Archives of Orthopaedic and Trauma Surgery (2023)

  16. Article

    Open Access

    Allografts: expanding the surgeon’s armamentarium

    In Germany, bone allografts are widely used and their application in clinics has increased over the years. Successful use of allografts depends on many factors such as the procurement, processing, sterilizatio...

    Norus Ahmed, Volker Eras, Axel Pruß, Carsten Perka, Jan Brune in Cell and Tissue Banking (2023)

  17. No Access

    Article

    Standard- und Spezialinlays in primärer Hüftendoprothetik

    Die Instabilität ist eine der Hauptursachen für Revisionen von Hüftendoprothesen. Durch spezielle Polyethyleninlays soll die Gelenkstabilität des Hüftgelenkersatzes verbessert werden. Im Juli 2022 wurde im The Bo...

    Paula Krull, Arnd Steinbrück, Alexander W. Grimberg, Oliver Melsheimer in Die Orthopädie (2023)

  18. No Access

    Article

    Abrieberkrankungen und deren Effekte auf das umliegende Gewebe

    Die Abrieberkrankung beschreibt den Effekt des Implantatabriebs auf das umliegende Gewebe und das damit einhergehende Wohlbefinden des Patienten. Sie ist multifaktoriell durch die Art der Gleitpaarung, die Kop...

    Dr. Stefanie Donner, Carsten Perka, Veit Krenn, Melanie-Jasmin Ort in Die Orthopädie (2023)

  19. No Access

    Article

    Injectable autologous chondrocyte implantation in acetabular cartilage defects: 2-year minimum clinical and MRI results

    Early results using injectable autologous chondrocyte implantation (ACI) for the treatment of full thickness acetabular cartilage defects have been promising. However, so far there is no information on radiolo...

    David R. Krueger, Alexander D. J. Baur in Archives of Orthopaedic and Trauma Surgery (2023)

  20. Article

    Open Access

    Mechanical failure of total hip arthroplasties and associated risk factors

    Mechanical failure of total hip arthroplasties is a rare but devastating complication. With increasing numbers in primary arthroplasty implantation, revision surgeries are indicated more often. Therefore, unde...

    Henrik C. Bäcker, Chia H. Wu, Arne Kienzle in Archives of Orthopaedic and Trauma Surgery (2023)

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