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The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
B cells arise via a precise developmental pathway. Goodnow and Beutler report that mice bearing mutations in Atp11c, which encodes a phosphatidylserine 'flippase', have defective B cell generation in the adult bo...
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Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
Lymphocytes travel throughout the body to carry out immune surveillance and participate in inflammatory reactions. Their path takes them from blood through tissues into lymph and back to blood. Molecules that ...