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  1. Article

    Open Access

    Early prediction of severe retinopathy of prematurity requiring laser treatment using physiological data

    Early risk stratification for develo** retinopathy of prematurity (ROP) is essential for tailoring screening strategies and preventing abnormal retinal development. This study aims to examine the ability of ...

    Jarinda A. Poppe, Sean P. Fitzgibbon, H. Rob Taal, Sjoukje E. Loudon in Pediatric Research (2023)

  2. Article

    Open Access

    Early life inflammation is associated with spinal cord excitability and nociceptive sensitivity in human infants

    Immune function and sensitivity to pain are closely related, but the association between early life inflammation and sensory nervous system development is poorly understood—especially in humans. Here, in term-...

    Maria M. Cobo, Gabrielle Green, Foteini Andritsou, Luke Baxter in Nature Communications (2022)

  3. Article

    Open Access

    Author Correction: A tool for functional brain imaging with lifespan compliance

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Ryan M. Hill, Elena Boto, Niall Holmes, Caroline Hartley in Nature Communications (2019)

  4. Article

    Open Access

    A tool for functional brain imaging with lifespan compliance

    The human brain undergoes significant functional and structural changes in the first decades of life, as the foundations for human cognition are laid down. However, non-invasive imaging techniques to investiga...

    Ryan M. Hill, Elena Boto, Niall Holmes, Caroline Hartley in Nature Communications (2019)

  5. Article

    Open Access

    Birth experience in newborn infants is associated with changes in nociceptive sensitivity

    Vaginal birth prepares the fetus for postnatal life. It confers respiratory, cardiovascular and homeostatic advantages to the newborn infant compared with elective cesarean section, and is reported to provide ...

    Severin Kasser, Caroline Hartley, Hanna Rickenbacher, Noemi Klarer in Scientific Reports (2019)

  6. No Access

    Chapter

    Neuroimaging of Paediatric Pain

    Pain during childhood can have a major impact on a child’s quality of life and development. However, given the changes in neurobiology, pharmacodynamics and pain assessment across this wide age range, from pre...

    Caroline Hartley, Rebeccah Slater in Neuroimaging of Pain (2017)

  7. Article

    Open Access

    The relationship between nociceptive brain activity, spinal reflex withdrawal and behaviour in newborn infants

    Measuring infant pain is complicated by their inability to describe the experience. While nociceptive brain activity, reflex withdrawal and facial grimacing have been characterised, the relationship between th...

    Caroline Hartley, Sezgi Goksan, Ravi Poorun, Kelly Brotherhood in Scientific Reports (2015)

  8. Article

    Open Access

    Identification of Criticality in Neuronal Avalanches: II. A Theoretical and Empirical Investigation of the Driven Case

    The observation of apparent power laws in neuronal systems has led to the suggestion that the brain is at, or close to, a critical state and may be a self-organised critical system. Within the framework of sel...

    Caroline Hartley, Timothy J Taylor in The Journal of Mathematical Neuroscience (2014)

  9. Article

    Open Access

    Identification of Criticality in Neuronal Avalanches: I. A Theoretical Investigation of the Non-driven Case

    In this paper, we study a simple model of a purely excitatory neural network that, by construction, operates at a critical point. This model allows us to consider various markers of criticality and illustrate ...

    Timothy J Taylor, Caroline Hartley in The Journal of Mathematical Neuroscience (2013)