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Open AccessEarly prediction of severe retinopathy of prematurity requiring laser treatment using physiological data
Early risk stratification for develo** retinopathy of prematurity (ROP) is essential for tailoring screening strategies and preventing abnormal retinal development. This study aims to examine the ability of ...
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Article
Open AccessEarly life inflammation is associated with spinal cord excitability and nociceptive sensitivity in human infants
Immune function and sensitivity to pain are closely related, but the association between early life inflammation and sensory nervous system development is poorly understood—especially in humans. Here, in term-...
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Article
Open AccessAuthor Correction: A tool for functional brain imaging with lifespan compliance
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessA tool for functional brain imaging with lifespan compliance
The human brain undergoes significant functional and structural changes in the first decades of life, as the foundations for human cognition are laid down. However, non-invasive imaging techniques to investiga...
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Article
Open AccessBirth experience in newborn infants is associated with changes in nociceptive sensitivity
Vaginal birth prepares the fetus for postnatal life. It confers respiratory, cardiovascular and homeostatic advantages to the newborn infant compared with elective cesarean section, and is reported to provide ...
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Neuroimaging of Paediatric Pain
Pain during childhood can have a major impact on a child’s quality of life and development. However, given the changes in neurobiology, pharmacodynamics and pain assessment across this wide age range, from pre...
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Article
Open AccessThe relationship between nociceptive brain activity, spinal reflex withdrawal and behaviour in newborn infants
Measuring infant pain is complicated by their inability to describe the experience. While nociceptive brain activity, reflex withdrawal and facial grimacing have been characterised, the relationship between th...
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Article
Open AccessIdentification of Criticality in Neuronal Avalanches: II. A Theoretical and Empirical Investigation of the Driven Case
The observation of apparent power laws in neuronal systems has led to the suggestion that the brain is at, or close to, a critical state and may be a self-organised critical system. Within the framework of sel...
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Open AccessIdentification of Criticality in Neuronal Avalanches: I. A Theoretical Investigation of the Non-driven Case
In this paper, we study a simple model of a purely excitatory neural network that, by construction, operates at a critical point. This model allows us to consider various markers of criticality and illustrate ...