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    Protocol

    Quantifying ABCA1/apoA-1 Signaling Pathways with AFM Imaging and Lipidomic Analysis

    The role of lipid metabolic pathways in the pathophysiology of primary open-angle glaucoma (POAG) has been thoroughly elucidated, with pathways involved in lipid-related disorders such as hypercholesterolemia ...

    Carolina Cruz-Wegener, Jonah Kutell, Louay Aldaher, Noa deHaseth in Lipid Signalling (2024)

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    Protocol

    Downregulation of ATP8B2 to Assess Plasmalogen Distribution and Far1 Expression in Primary Trabecular Meshwork Cells

    The trabecular meshwork (TM) from primary open-angle glaucoma (POAG) cases has been found to contain decreased levels of intracellular plasmalogens. Plasmalogens are a subset of lipids involved in diverse cell...

    Ishan Chaplot, Carolina Cruz-Wegener, Maria D. Cabrera Gonzalez in Lipid Signalling (2024)