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Article
Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...
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Article
Open AccessCPMI-ChatGLM: parameter-efficient fine-tuning ChatGLM with Chinese patent medicine instructions
Chinese patent medicine (CPM) is a typical type of traditional Chinese medicine (TCM) preparation that uses Chinese herbs as raw materials and is an important means of treating diseases in TCM. Chinese patent ...
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Article
Open AccessCepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery
Cepharanthine is a secondary metabolite isolated from Stephania. It has been reported that it has anti-conronaviruses activities including severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Here, we as...
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Article
Open AccessThe PAPSS1 gene is a modulator of response to cisplatin by regulating estrogen receptor alpha signaling activity in ovarian cancer cells
Cancer cells may develop resistance to cisplatin by various mechanisms. Yet, the exact mechanism of cisplatin in ovarian cancer remains unclear. Recent studies have shown that 3’-phospoadenosine 5’-phosphosulf...
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Article
Open AccessRisk factors for avascular necrosis in patients with systemic lupus erythematosus: a multi-center cohort study of Chinese SLE Treatment and Research Group (CSTAR) Registry XXII
Avascular necrosis is a common organ damage in SLE patients, which can influence patients’ life quality. Conflicting results exist in risk factors of AVN in SLE patients. The aim of this study was to illustrat...
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Article
Open AccessGenome-wide identification of Aux/IAA and ARF gene families reveal their potential roles in flower opening of Dendrobium officinale
The auxin indole-3-acetic acid (IAA) is a vital phytohormone that influences plant growth and development. Our previous work showed that IAA content decreased during flower development in the medicinally impor...
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Article
Open AccessContributions of oceanic and continental AAM to interannual variation in ΔLOD with the detection of 2020–2021 La Nina event
As a strong climate element on interannual scales, the El Nino-Southern Oscillation (ENSO) is a major component of global weather and climate change, and it is also closely related to the interannual atmospher...
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Article
Open AccessChronic spinal cord injury repair by NT3-chitosan only occurs after clearance of the lesion scar
Spinal cord injury (SCI) is a severe damage usually leading to limb dysesthesia, motor dysfunction, and other physiological disability. We have previously shown that NT3-chitosan could trigger an acute SCI rep...
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Article
A review on Ti3C2Tx-based nanomaterials: synthesis and applications in gas and humidity sensors
Ti3C2Tx, which is a novel two-dimensional (2D) material, has received enormous interest in the field of sensor technology due to its large surface area, excellent electrical conductivity, and abundant active surf...
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Open AccessOn the ~ 7 year periodic signal in length of day from a frequency domain stepwise regression method
The intradecadal variations in length-of-day (LOD) and their time-varying characteristics still need to be further studied. Given that the corresponding signal periods on the intradecadal scales are quite clos...
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Open AccessChinese SLE Treatment and Research Group Registry (CSTAR) XIII: prevalence and risk factors for chronic scarring alopecia in patients with systemic lupus erythematosus
Scarring alopecia in systemic lupus erythematosus (SLE) patients caused reduced life quality and prolonged disease course. This case-control study aims to survey the prevalence of scarring alopecia during the ...
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Open AccessMultigene phylogeny of the family Cordycipitaceae (Hypocreales): new taxa and the new systematic position of the Chinese cordycipitoid fungus Paecilomyces hepiali
The phylogeny and systematics of cordycipitoid fungi have been extensively studied in the last two decades. However, systematic positions of some taxa in the family Cordycipitaceae have not yet been thoroughly...
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Article
Open AccessRepeated CyberKnife stereotactic body radiation therapy in hepatocellular carcinoma
To explore the survival and side effects of repeated CyberKnife stereotactic body radiation therapy (CK-SBRT) on hepatocellular carcinoma patients.
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Article
Coherently driving a single quantum two-level system with dichromatic laser pulses
The excitation of individual two-level quantum systems using an electromagnetic field is an elementary tool of quantum optics, with widespread applications across quantum technologies. The efficient excitation...
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Article
Open AccessDecreased expression of STING predicts poor prognosis in patients with gastric cancer
STING (stimulator of interferon genes) has recently been found to play an important role in host defenses against virus and intracellular bacteria via the regulation of type-I IFN signaling and innate immunity...
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Article
Open AccessHigh expression of GFAT1 predicts poor prognosis in patients with pancreatic cancer
Pancreatic cancer is one of the most lethal of all types of cancer, with the 5-year survival rate ranging only at 6–7%. The aberrant glucose metabolism is one of the hallmarks of cancer cells, and as a branch ...
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Article
Two genes conferring resistance to Pythium stalk rot in maize inbred line Qi319
Stalk rots are destructive diseases in maize around the world, and are most often caused by the pathogen Pythium, Fusarium and other fungi. The most efficient management for controlling stalk rots is to breed res...
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Article
Synthesis, characterization and application of organic-inorganic hybrid and carbaryl-imprinted capillary monolithic column
Organic-inorganic hybrid and carbaryl-imprinted capillary monolith was synthesized via methacrylic acid(MAA) as functional monomer, γ-methacryloxypropyltrimethoxysilane(γ-MAPS) as crosslinker and carbaryl as temp...
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Article
Genome characterization of a novel porcine bocavirus
Using a high-throughput DNA sequencing method, one DNA sequence (contig01006), suspected to belong to a novel porcine bocavirus (PBoV), was found with a high rate of detection (19.6 %) in fecal samples from he...
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Article
Biphasic regulation of P-glycoprotein function and expression by NO donors in Caco-2 cells
To investigate the effects of nitric oxide (NO) donors on the function and expression of P-glycoprotein (P-gp) in Caco-2 cells.
