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  1. No Access

    Article

    2-BFI Provides Neuroprotection Against Fluorosis by Stabilizing Endoplasmic Reticulum–Mitochondria Contact Sites and Inhibiting Activation of the NLRP3 Inflammasome

    2-(2-benzofu-ranyl)-2-imidazoline (2-BFI) is a drug that has attracted much attention in recent years. It has a therapeutic effect on brain diseases in animal models such as Alzheimer’s disease and cerebral in...

    Rui Chen, Wan Xu, Yifu Sun, Rongrong Zhi, Peng **e, Zhongwen Zhi… in Neurochemical Research (2023)

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    Article

    The p38/CYLD Pathway is Involved in Necroptosis Induced by Oxygen-glucose Deprivation Combined with ZVAD in Primary Cortical Neurons

    Recently, necroptosis, a form of programmed necrosis, has been widely studied. It has previously been shown that knockout of lysine 63 deubiquitinase CYLD significantly inhibits necroptosis in other cell lines...

    Tao Feng, WeiWei Chen, CaiYi Zhang, Jie **ang, HongMei Ding… in Neurochemical Research (2017)

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    Article

    The Inhibition of ERK Activation Mediates the Protection of Necrostatin-1 on Glutamate Toxicity in HT-22 Cells

    Receptor-interacting protein 1 (RIP1), a molecular switch protein from apoptosis to necroptosis, is regarded to play an essential role in necroptotic cell death. Although the increased RIP1 activity induced by...

    Min Zhang, Jizhen Li, Runlu Geng, Wei Ge, Yanlong Zhou… in Neurotoxicity Research (2013)