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  1. Article

    Open Access

    Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solution

    Retroviral integrases (INs) catalyze the integration of viral DNA in the chromosomal DNA of the infected cell. This reaction requires the multimerization of IN to coordinate a nucleophilic attack of the 3’ end...

    Daniel R Henriquez, Caifeng Zhao, Haiyan Zheng, José J Arbildua… in BMC Structural Biology (2013)

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