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  1. Article

    Open Access

    Inadequate linear catch-up growth in children born small for gestational age: Influencing factors and underlying mechanisms

    A minority of children born small for gestational age (SGA) may experience catch-up growth failure and remain short in adulthood. However, the underlying causes and mechanisms of this phenomenon are not yet fu...

    Anran Tian, Fucheng Meng, Sujuan Li in Reviews in Endocrine and Metabolic Disorde… (2024)

  2. Article

    Open Access

    Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration

    Intervertebral disc degeneration (IVDD) is a major cause of morbidity and disability. Our study aimed to investigate the potential of cartilage oligomeric matrix protein (COMP) and ADAMTS7 (A disintegrin and m...

    **g-Yu Ding, Xu Yan, Ren-Jie Zhang, Hua-Qing Zhang in European Journal of Medical Research (2024)

  3. No Access

    Article

    FSTL1 Accelerates Nucleus Pulposus Cell Senescence and Intervertebral Disc Degeneration Through TLR4/NF-κB Pathway

    Intervertebral disc degeneration (IVDD) is a major contributor to low back pain (LBP), and inflammatory factors play crucial roles in its pathogenesis. Follistatin-like 1 (FSTL1) has been reported to induce an...

    Xu Yan, **g-Yu Ding, Ren-Jie Zhang, Hua-Qing Zhang, Liang Kang in Inflammation (2024)

  4. No Access

    Article

    Efficacy and Safety of Different Doses of Rivaroxaban and Risk Factors for Bleeding in Elderly Patients with Venous Thromboembolism: A Real-World, Multicenter, Observational, Cohort Study

    Venous thromboembolism (VTE) consists of deep vein thrombosis (DVT) and pulmonary embolism (PE). Rivaroxaban is a direct oral anticoagulant (DOAC) inhibiting activated coagulation factor X (FXa), and exerts se...

    Kepeng Lu, Qian-Qian Liao, Ke-Wei Zhu, Ying Yao, **ao-Jiao Cui in Advances in Therapy (2024)

  5. No Access

    Article

    Prokineticin 2 as a potential biomarker for the diagnosis of Kawasaki disease

    Kawasaki disease is a pressing acute self-limiting inflammatory disorder disease which lack of specific biomarkers. Our research aims to investigate the serum expression of a novel immune regulator PK2 in chil...

    Li Zeng, Cai Wang, Zhixin Song, Qian Liu, Dapeng Chen in Clinical and Experimental Medicine (2023)

  6. No Access

    Article

    Artificial intelligence–based prediction of cervical lymph node metastasis in papillary thyroid cancer with CT

    To develop an artificial intelligence (AI) system for predicting cervical lymph node metastasis (CLNM) preoperatively in patients with papillary thyroid cancer (PTC) based on CT images.

    Cai Wang, Pengyi Yu, Haicheng Zhang, **ao Han, Zheying Song in European Radiology (2023)

  7. Article

    Open Access

    Efficacy and Safety of Triptorelin 3-Month Formulation in Chinese Children with Central Precocious Puberty: A Phase 3, Open-Label, Single-Arm Study

    Triptorelin is available as 1- and 3-month prolonged-release (PR) formulations; at the time of the study, only the former was approved for central precocious puberty (CPP) in China. This study assessed the eff...

    ** Luo, Cai Zhang, Yu Yang, Xu Xu, **nran Cheng, Haiyan Wei in Advances in Therapy (2023)

  8. Article

    Open Access

    Risk factors of peripheral venous catheter-related complication and infection in children with bronchopneumonia

    To investigate the risk factors associated with the peripheral venous catheter-related complication and infection in children with bronchopneumonia.

    Hong-mei Li, Li-li Wan, Cai-xiang **, Guo-ying Zhang, Hui Yang in BMC Infectious Diseases (2023)

  9. Article

    Open Access

    BUN level is associated with cancer prevalence

    Blood urea nitrogen (BUN) was an important biomarker for the development and prognosis of many diseases. Numerous studies had demonstrated that BUN had a strong relationship with long-term mortality, survival ...

    Cai Wang, Hao Sun, ** Liu in European Journal of Medical Research (2023)

  10. No Access

    Article

    TRIM25 promotes temozolomide resistance in glioma by regulating oxidative stress and ferroptotic cell death via the ubiquitination of keap1

    Resistance to temozolomide (TMZ) remains an important cause of treatment failure in patients with glioblastoma multiforme (GBM). TRIM25, as a tripartite motif-containing (TRIM) family member, plays a significa...

    Jianwei Wei, Li Wang, Yuyan Zhang, Ting Sun, Cai Zhang, Zhonglan Hu in Oncogene (2023)

  11. No Access

    Article

    Ultrasound-based deep learning in the establishment of a breast lesion risk stratification system: a multicenter study

    To establish a breast lesion risk stratification system using ultrasound images to predict breast malignancy and assess Breast Imaging Reporting and Data System (BI-RADS) categories simultaneously.

    Yang Gu, Wen Xu, Ting Liu, **ng An, Jiawei Tian, Haitao Ran in European Radiology (2023)

  12. Article

    Open Access

    Medium and long-term radiographic and clinical outcomes of Dynesys dynamic stabilization versus instrumented fusion for degenerative lumbar spine diseases

    Dynesys stabilization (DS) is utilized to preserve mobility at the instrumental segments and prevent adjacent segment pathology in clinical practice. However, the advantages of DS method in medium and long-ter...

    Lu-** Zhou, Ren-Jie Zhang, Jia-Qi Wang, Hua-Qing Zhang, ** Shang in BMC Surgery (2023)

  13. Article

    Open Access

    Posterior osteosynthesis with a new self-designed lateral mass screw-plate system for unstable atlas burst fractures

    In the treatment of unstable atlas fractures using the combined anterior–posterior approach or the posterior monoaxial screw-rod system, factors such as severe trauma or complex surgical procedures still need ...

    Kun Yang, He-gang Niu, Hui Tao, Chang Liu, Yun Cao, Wei Li in BMC Musculoskeletal Disorders (2023)

  14. Article

    Open Access

    The sirtuin family in health and disease

    Sirtuins (SIRTs) are nicotine adenine dinucleotide(+)-dependent histone deacetylases regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in numerous biological processes. Cur...

    Qi-Jun Wu, Tie-Ning Zhang, Huan-Huan Chen in Signal Transduction and Targeted Therapy (2022)

  15. Article

    Open Access

    Survival outcome assessment for triple-negative breast cancer: a nomogram analysis based on integrated clinicopathological, sonographic, and mammographic characteristics

    This study aimed to incorporate clinicopathological, sonographic, and mammographic characteristics to construct and validate a nomogram model for predicting disease-free survival (DFS) in patients with triple-...

    Dan-li Sheng, **-gang Shen, Zhao-ting Shi, Cai Chang, Jia-wei Li in European Radiology (2022)

  16. Article

    Open Access

    Deep learning based on ultrasound images assists breast lesion diagnosis in China: a multicenter diagnostic study

    Studies on deep learning (DL)-based models in breast ultrasound (US) remain at the early stage due to a lack of large datasets for training and independent test sets for verification. We aimed to develop a DL ...

    Yang Gu, Wen Xu, Bin Lin, **ng An, Jiawei Tian, Haitao Ran in Insights into Imaging (2022)

  17. Article

    Open Access

    Predictors of accurate intrapedicular screw placement in single-level lumbar (L4-5) fusion: robot-assisted pedicle screw, traditional pedicle screw, and cortical bone trajectory screw insertion

    The superiorities in proximal facet joint protection of robot-assisted (RA) pedicle screw placement and screw implantation via the cortical bone trajectory (CBT) have rarely been compared. Moreover, findings o...

    Hua-Qing Zhang, Can-Can Wang, Ren-Jie Zhang, Lu-** Zhou, Chong-Yu Jia in BMC Surgery (2022)

  18. Article

    Correction to: Prediction for pathological and immunohistochemical characteristics of triple‑negative invasive breast carcinomas: the performance comparison between quantitative and qualitative sonographic feature analysis

    Jia‑wei Li, Yu‑cheng Cao, Zhi‑** Zhao, Zhao‑ting Shi, **ao‑qian Duan in European Radiology (2022)

  19. No Access

    Article

    Prediction for pathological and immunohistochemical characteristics of triple-negative invasive breast carcinomas: the performance comparison between quantitative and qualitative sonographic feature analysis

    Sonographic features are associated with pathological and immunohistochemical characteristics of triple-negative breast cancer (TNBC). To predict the biological property of TNBC, the performance using quantita...

    Jia-wei Li, Yu-cheng Cao, Zhi-** Zhao, Zhao-ting Shi, **ao-qian Duan in European Radiology (2022)

  20. Article

    Open Access

    Rates and risk factors of intrapedicular accuracy and cranial facet joint violation among robot-assisted, fluoroscopy-guided percutaneous, and freehand techniques in pedicle screw fixation of thoracolumbar fractures: a comparative cohort study

    Robot-assisted (RA) technique has been increasingly applied in clinical practice, providing promising outcomes of inserting accuracy and cranial facet joint protection. However, studies comparing this novel me...

    Ren-Jie Zhang, Lu-** Zhou, Hua-Qing Zhang, Peng Ge, Chong-Yu Jia in BMC Surgery (2022)

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