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Article
Structures of medium-sized silicon clusters
Silicon is the most important semiconducting material in the microelectronics industry. If current miniaturization trends continue, minimum device features will soon approach the size of atomic clusters. In th...
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Article
Photoluminescence of fullerene[60] in ultrathin ordered multilayers: The dissociation of molecular aggregation
The aggregation behavior of a substituted fullerene compound, 1-benzyl-2-hydro[60]fullerene (C60-Be), in Z-type ultrathin ordered (e.g. LB) multilayers has been studied by UV-vis absorption, steady state and time...
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Article
JNK phosphorylates paxillin and regulates cell migration
The c-Jun amino-terminal kinase (JNK) is generally thought to be involved in inflammation, proliferation and apoptosis1,2. Accordingly, its substrates are transcription factors and anti-apoptotic proteins2. Howev...
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Article
The cause of crustal deformation in the vicinity of Zhangbei earthquake area: Discussion with Wang Chao and Zhang Hong et al.
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Article
Composition, structure and mechanical properties of several natural cellular materials
The stem piths of sunflower, kaoliang and corn are natural cellular materials. In this paper, the contents of the compositions of these piths are determined and their cell shapes and structures are examined th...
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Article
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
Escherichia coli AlkB and its human homologues ABH2 and ABH3 repair DNA/RNA base lesions by using a direct oxidative dealkylation mechanism. ABH2 has the primary role of guarding mammalian genomes against 1-meA d...
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Article
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase
The AlkB type proteins are demethylases that are thought to play a part in DNA repair by oxidatively removing methyl adducts on DNA, RNA and histones. Yi et al. have determined the structure of AlkB oxygenase cry...
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Article
Open AccessCritical role of Toll-like receptor signaling in NK cell activation
Toll-like receptors (TLRs) and NK cell receptors are the most important receptor superfamilies in innate immunity. TLRs act as the sensor of external pathogens, while NK cells detect alterations in endogenous ...
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Article
Open AccessPerformance of breast cancer screening methods and modality among Chinese women: a report from a society-based breast screening program (SBSP) in Shanghai
To evaluate the screening performance of individual and combined use of clinical breast examination, ultrasonography and mammography in Chinese women, we conducted a biennial breast cancer screening program am...
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Article
Open AccessOn-the-fly machine-learning for high-throughput experiments: search for rare-earth-free permanent magnets
Advanced materials characterization techniques with ever-growing data acquisition speed and storage capabilities represent a challenge in modern materials science and new procedures to quickly assess and analy...
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Article
Open AccessExploration of tetrahedral structures in silicate cathodes using a motif-network scheme
Using a motif-network search scheme, we studied the tetrahedral structures of the dilithium/disodium transition metal orthosilicates A2MSiO4 with A = Li or Na and M = Mn, Fe or Co. In addition to finding all prev...
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Article
Open AccessStructural insights into HetR−PatS interaction involved in cyanobacterial pattern formation
The one-dimensional pattern of heterocyst in the model cyanobacterium Anabaena sp. PCC 7120 is coordinated by the transcription factor HetR and PatS peptide. Here we report the complex structures of HetR binding ...
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Article
Open Access‘Crystal Genes’ in Metallic Liquids and Glasses
We analyze the underlying structural order that transcends liquid, glass and crystalline states in metallic systems. A genetic algorithm is applied to search for the most common energetically favorable packing...
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Article
Open AccessHepatitis B virus inhibits intrinsic RIG-I and RIG-G immune signaling via inducing miR146a
Previous studies showed that hepatitis B virus (HBV), as a latency invader, attenuated host anti-viral immune responses. miRNAs were shown to be involved in HBV infection and HBV-related diseases, however, the...
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Article
Open AccessMiR 3180-5p promotes proliferation in human bladder smooth muscle cell by targeting PODN under hydrodynamic pressure
Human bladder smooth muscle cells (HBSMCs) were subjected to pressure cycles of up to 200 cm H2O to a pressure of 0 cm H2O for 24 hours. The total RNA extracted from each group was subjected to microarray analysi...
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Article
Open AccessSize Switchable Supramolecular Nanoparticle Based on Azobenzene Derivative within Anionic Pillar[5]arene
A photo/thermal-switchable supramolecular nanoparticles assembly has been constructed based on an inclusion complex between anionic pillar[5]arene 2C-WP5A and azobenzene derivative Azo-py-OMe (G). The novel anion...
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Article
Open AccessIncreased Renal Clearance of Rocuronium Compensates for Chronic Loss of Bile Excretion, via upregulation of Oatp2
Requirement for rocuronium upon surgery changes only minimally in patients with end-stage liver diseases. Our study consisted of both human and rat studies to explore the reason. The reduction rate of rocuroni...
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Article
Open AccessThe molecular basis of talin2’s high affinity toward β1-integrin
Talin interacts with β-integrin tails and actin to control integrin activation, thus regulating focal adhesion dynamics and cell migration. There are two talin genes, Tln1 and Tln2, which encode talin1 and talin2...
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Article
Open AccessHigh photon-to-heat conversion efficiency in the wavelength region of 250–1200 nm based on a thermoelectric Bi2Te3 film structure
In this work, 4-layered SiO2/Bi2Te3/SiO2/Cu film structures were designed and fabricated and the optical properties investigated in the wavelength region of 250–1200 nm for their promising applications for direct...
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Article
Open AccessH2S regulates endothelial nitric oxide synthase protein stability by promoting microRNA-455-3p expression
The aims of the present study are to determine whether hydrogen sulfide (H2S) is involved in the expression of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) production, and to identify the role o...