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Article
Open AccessAuditorische Stimulation während des Schlafs
Die Insomnie, d. h. eine Ein- und/oder Durchschlafstörung, die sich negativ auf die Leistungsfähigkeit und Tagesbefindlichkeit auswirkt, ist eine der häufigsten Erkrankungen in der Allgemeinbevölkerung. Sie wi...
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Article
Open AccessAuthor Correction: Post-stroke insomnia in community-dwelling patients with chronic motor stroke: Physiological evidence and implications for stroke care
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper
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Article
Open AccessPost-stroke insomnia in community-dwelling patients with chronic motor stroke: Physiological evidence and implications for stroke care
Questionnaire studies suggest that stroke patients experience sustained problems with sleep and daytime sleepiness, but physiological sleep studies focussing specifically on the chronic phase of stroke are lac...
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Article
S3-Leitlinie Nicht erholsamer Schlaf/Schlafstörungen
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Article
Schlaf, Lernen und Gedächtnis: Relevanz für Psychiatrie und Psychotherapie
Schlaf ist ein Zustand, der die Konsolidierung kürzlich erworbener Gedächtnisinhalte optimiert. Daher könnten Schlafstörungen zu Gedächtnisverminderungen bei psychiatrischen Erkrankungen wie der Depression ode...
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Article
Insomnische Störungen
Aktuell gebräuchliche diagnostische Systeme wie ICD-10 oder DSM-IV werden der Komplexität und Heterogenität insomnischer Störungen nicht gerecht. Mit dem ICSD-2 und den Research Diagnostic Criteria (RDC) wurde...
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Article
Substanzinduzierte Schlafstörungen und Schlafmittelmissbrauch
Die Einnahme einer Vielzahl von Substanzen kann sich negativ auf den Schlaf auswirken. Dazu gehören die in unserer Gesellschaft häufig konsumierten Genussdrogen wie Koffein, Nikotin und Alkohol. Illegale Droge...
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Article
Verarbeitung schlafbezogener Stimuli
Vorangegangene Arbeiten legen nahe, dass Menschen mit einem gestörten Nachtschlaf, insbesondere bei Vorliegen einer primären Insomnie, eine verstärkte Zuwendung der Aufmerksamkeit zu schlafbezogenen Stimuli ze...
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Chapter and Conference Paper
Fetal Hematopoietic Stem Cells: In Vitro Expansion and Transduction Using Lentiviral Vectors
Umbilical cord blood (CB), remaining in the placenta at delivery, is rich in hematopoietic stem and progenitor cells. Compared with adult peripheral blood, the content of CD34+ and CD34+CD38− cells in CB is appro...
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Article
Successful treatment of refractory acquired pure red cell aplasia (PRCA) by allogeneic bone marrow transplantation
This case describes a 16-year-old woman treated successfully by a bone marrow transplant from her HLA-identical brother for refractory acquired pure red cell aplasia. Conditioning was as for severe aplastic an...
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Chapter
Peripheral Blood Precursor Cell Transplants Across a Major Histocompatibility Barrier in Rabbits
Peripheral blood precursor cells (PBPC) are used with increasing frequency as a source for hematopoietic transplants and have mainly replaced autologous bone marrow transplants. First clinical and experimental...
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Article
Cytokine serum levels during treatment with high-dose recombinant human IL-3 in a patient with severe aplastic anemia
A 37-year-old woman with severe aplastic anemia (SAA), who had relapsed 6 years after antilymphocyte globulin therapy, was treated with intravenous recombinant human IL-3 (4μg/kg/d) for 21 days. Subsequently, lon...
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Article
Abstract
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Article
Cytotoxic and stimulatory effects of antilymphocyte globulin (ALG) on hematopoiesis
Four different preparations of antilymphocyte/antithymocyte globulin were tested in vitro for their toxicity to lymphocytes and to hematopoietic precursor cells, depending on concentration and time. Complete l...
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Chapter
Treatment of Severe Aplastic Anemia: A 12-Year Follow-Up of Patients after Bone Marrow Transplantation or after Therapy with Antilymphocyte Globulin
Of 145 patients with severe aplastic anemia (SAA) treated in Basel from 1976 to January 1988, 34 with HLA identical siblings had bone marrow transplants (BMT) and 111 were treated with antilymphocyte globulin ...
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Chapter
Treatment of Severe Aplastic Anemia (SAA) with Bone Marrow Transplantation (BMT) or Immunosuppression: A Report of the EBMT SAA Working Party
This is a comparison of 218 patients with severe aplastic anemia (SAA) treated by allogeneic bone marrow transplantation (BMT) from HLA-identical sibling donors and 291 patients with SAA treated with immunosup...
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Article
Treatment of thrombocytosis in myeloproliferative disorders with interferon alpha-2a
In an open prospective pilot trial, we tested the effect of recombinant interferon alpha-2a (rIFN alpha-2a) on thrombocytosis in myeloproliferative disorders (MPD). Since October 1986, 13 patients with MPD (4 ...
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Article
Secondary leukemia after severe aplastic anemia
We describe a patient with acute myeloid leukemia (AML) occurring 5 years after successful treatment of severe aplastic anemia (SAA) with antilymphocyte globulin (ALG). Four years after ALG, SAA had relapsed. ...
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Article
Abundant macrophage growth in culture from patients with chronic myelogenous leukemia: a risk factor for Graft-versus-Host Disease after bone marrow transplantation
Peripheral blood cultures of hemopoietic precursor cells from 30 patients with chronic myelogenous leukemia showed different growth patterns before bone marrow transplantation. A strong increase of free and cl...
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Article
Immunoadsorption for removal of anti-A and anti-B blood group antibodies in ABO-incompatible bone marrow transplantation
About 10–15 percent of all patients undergoing allogeneic bone marrow transplantation have a major ABO-incompatibility with their donors. The risk of acute hemolytic reactions due to the infusion of an incompa...