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  1. Article

    Open Access

    Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis

    The objective of this study was to determine the molecular mechanisms responsible for cellular radiosensitivity in two human fibroblast cell lines 84BR and 175BR derived from two cancer patients.

    G Ulus-Senguloglu, C F Arlett, P N Plowman, J Parnell, N Patel… in British Journal of Cancer (2012)

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  2. Article

    Open Access

    Telomerase activity in melanoma and non-melanoma skin cancer

    Telomeres are specialized structures consisting of repeat arrays of TTAGGGn located at the ends of chromosomes. They are essential for chromosome stability and, in the majority of normal somatic cells, telomeres ...

    C N Parris, S Jezzard, A Silver, R MacKie, J M McGregor… in British Journal of Cancer (1999)

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    Article

    Intravesical chemotherapy: Combination with dimethyl sulfoxide does not enhance cytotoxicity in vitro

    There is evidence that dimethyl sulfoxide (DMSO) can increase the anticancer activity of chemotherapeutic drugs. As DMSO is instilled into the bladder for interstitial cystitis, it could be readily adopted in ...

    L. Walker, M. C. Walker, C. N. Parris, J. R. W. Masters in Urological Research (1988)

  4. No Access

    Article

    Intravesical chemotherapy: Combination with tween 80 increases cytotoxicity in vitro

    Tween 80 was shown to enhance significantly the cytotoxic activities of the four drugs (adriamycin, epodyl, mitomycin-c, thiotepa) most frequently administered intravesically to treat superficial bladder cance...

    C. N. Parris, J. R. W. Masters, M. C. Walker, B. Newman, P. Riddle… in Urological Research (1987)

  5. No Access

    Article

    Intravesical chemotherapy: In vitro studies on the relationship between dose and cytotoxicity

    The relative importance of two variables, drug concentration and period of exposure, in relation to the therapeutic potential of intravesical chemotherapy was examined in an experimental system. A human bladde...

    M. C. Walker, J. R. W. Masters, C. N. Parris, P. J. Hepburn… in Urological Research (1986)