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Chapter and Conference Paper
Repeatability of Minimum and Maximum Density Testing on Clean and Fouled Ballast
Ballast material is a critical part of the safety of railways, such as padding tracks to prevent dynamic vibrations from causing trains to derail. The effectiveness of this material is closely tied to the perc...
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Article
Open AccessOverexpression of the RNA-binding proteins Lin28B and IGF2BP3 (IMP3) is associated with chemoresistance and poor disease outcome in ovarian cancer
RNA-binding proteins have an important role in messenger RNA (mRNA) regulation during tumour development and carcinogenesis. In the present study, we examined the insulin-like growth factor 2 mRNA-binding prot...
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Article
Molecular analysis on the shoot apical meristem of truncated leaf syndrome plantlets of oil palm (E. guineensis Jacq.)
Truncated leaf syndrome (TLS) is a vegetative somaclonal variant of oil palm that is regenerated from cultured somatic cells. Until now, there are no molecular clues associated to this abnormality. Forward and...
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Article
Gene expression of the oil palm transcription factor EgAP2-1 during fruit ripening and in response to ethylene and ABA treatments
A cDNA encoding an ERE-binding protein (EgAP2-1) was isolated from the oil palm fruit mesocarp treated with ethylene using yeast one-hybrid assay. EgAP2-1 belongs to the AP2 subfamily of the APETALA2/ethylene-...
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Article
Grail as a molecular determinant for the functions of the tumor suppressor p53 in tumorigenesis
The transcription factor p53 is a multifunctional tumor suppressor that arrests the cell cycle in response to stress and modulates the DNA repair process or induces apoptosis. The cellular level and activity o...
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Article
Sequence analysis and gene expression of putative oil palm chitinase and chitinase-like proteins in response to colonization of Ganoderma boninense and Trichoderma harzianum
Chitinases are glycosyl hydrolases that cleave the β-1,4-glycosidic linkages between N-acetylglucosamine residues in chitin which is a major component of fungal cell wall. Plant chitinases hydrolyze fungal chitin...
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Article
Comparative mineral and hormonal analyses of wild type and TLS somaclonal variant derived from oil palm (Elaeis guineensis Jacq. var. tenera) tissue culture
Comparative mineral and hormonal analyses were made on tissue culture derived truncated leaf syndrome and wild type oil palm seedlings. Mineral analysis confirmed that Boron, Zinc and chlorophyll levels were s...
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Article
Morpho-histological characterization of truncated leaf syndrome seedlings: an oil palm (E. guineensis Jacq.) somaclonal variant
A comparative phenotypic and morpho-histological study was carried out on tissue culture-derived truncated leaf syndrome (TLS) and wild-type oil palm seedlings to investigate their phenotypic and morpho-histol...
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Article
Identifying LRRC16B as an oncofetal gene with transforming enhancing capability using a combined bioinformatics and experimental approach
Oncofetal genes are expressed in embryos or fetuses, are downregulated or undetectable in adult tissues, and then re-expressed in tumors. Known oncofetal genes, such as AFP, GCB, FGF18, IMP-1 and SOX1, often have...
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Article
Efficacy of medical therapy in the initial management of acute primary angle closure in Asians
Recent studies have advocated the use of laser iridoplasty or paracentesis in the initial management of patients with acute primary angle closure (APAC). The aim of this study was to ascertain the effectivenes...
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Article
Open AccessHigh Frequency Plant Regeneration from Mature Seed of Elite, Recalcitrant Malaysian Indica Rice (Oryza Sativa L.) CV. MR 219
An efficient in vitro plant regeneration system was established for elite, recalcitrant Malaysian indica rice, Oryza sativa L. CV. MR 219 using mature seeds as explant on Murashige and Skoog and Chu N6 media cont...
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Article
Functional screening for salinity tolerant genes from Acanthus ebracteatus Vahl using Escherichia coli as a host
Salinity reduces plant growth and crop production globally. The discovery of genes in salinity tolerant plants will provide the basis for effective genetic engineering strategies, leading to greater stress tol...
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Article
Open AccessCo-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder
Recepteur d'Origine Nantais (RON) is a distinct receptor tyrosine kinase in the c-met proto-oncogene family. We examined the mutational and expression patterns of RON in eight human uroepithelial cell lines. Biol...
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Article
CNS aspergillosis with mycotic aneurysm, cerebral granuloma and infarction
We are reporting a case of an immunocompromised patient with invasive aspergillosis (IA) who developed aspergillotic granulomas and a mycotic aneurysm of the superior cerebellar artery. The route of infection ...
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Article
Suppurative salmonella thyroiditis in a patient with chronic lymphocytic leukemia
We describe an 82-year-old man with undiagnosed chronic lymphocytic leukemia (CLL) who presented with acute swelling of the thyroid goiter. Subsequent thyroid aspirate and blood culture yielded group B Salmone...
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Article
Open AccessMolecular diagnosis of primary liver cancer by microsatellite DNA analysis in the serum
Frequent loss of heterozygosity of microsatellites markers on specific chromosomal region have been reported in various types of primary human cancer. The same loss of heterozygosity has also been identified i...
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Article
Molecular biology of the plastidic phosphorylated serine biosynthetic pathway in Arabidopsis thaliana
Serine biosynthesis in plants proceeds by two pathways; the glycolate pathway which is associated with photorespiration and the pathway from 3-phosphoglycerate which is presumed to take place in the plastids....
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Article
Acute respiratory distress syndrome following intrathecal methotrexate administration: a case report and review of literature
Acute Respiratory distress syndrome (ARDS) is a rare complication following intrathecal (IT) injection of methotrexate (MTX) in adult acute lymphoblastic leukemia (ALL) patients. A 19-year-old man with ALL de...
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Article
Lymphoma of bone with initial presentation as a calvarial mass
A 21-year-old man was examined for a right frontal skull mass that had been present for 4 months. Excision biopsy of the mass revealed diffuse large B-cell lymphoma. Subsequent studies showed right preauricul...
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Article
Cerebral dural sinus thrombosis in acute lymphoblastic leukemia with early diagnosis by fast fluid-attenuated inversion recovery (FLAIR) MR image: a case report and review of the literature
Cerebral dural sinus thrombosis (CDST) is a very rare complication of acute lymphoblastic leukemia (ALL) in adult patients. A 23-year-old man with ALL developed dizziness, headache, diplopia, limb weakness, a...
