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  1. Article

    Open Access

    Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue transcriptomic approach

    Production conditions of layer chicken can vary in terms of temperature or diet energy content compared to the controlled environment where pure-bred selection is undertaken. The aim of this study was to bette...

    F. Jehl, C. Désert, C. Klopp, M. Brenet, A. Rau, S. Leroux, M. Boutin in BMC Genomics (2019)

  2. Article

    Open Access

    Rapid Discovery of De Novo Deleterious Mutations in Cattle Enhances the Value of Livestock as Model Species

    In humans, the clinical and molecular characterization of sporadic syndromes is often hindered by the small number of patients and the difficulty in develo** animal models for severe dominant conditions. Her...

    E. Bourneuf, P. Otz, H. Pausch, V. Jagannathan, P. Michot, C. Grohs in Scientific Reports (2017)

  3. Article

    Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept

    Evidence suggests that bacterial components in blood could play an early role in events leading to diabetes. To test this hypothesis, we studied the capacity of a broadly specific bacterial marker (16S rDNA) t...

    J. Amar, M. Serino, C. Lange, C. Chabo, J. Iacovoni, S. Mondot, P. Lepage in Diabetologia (2011)