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    Article

    Discontinuation of tyrosine kinase inhibitor in chronic myeloid leukemia: a retrospective cohort in east occitania

    Tyrosine kinase inhibitor (TKI) discontinuation in chronic phase chronic myeloid leukemia (CML) patients has been examined in a real-life setting in the east occitania region of France. We have collected sex, ...

    J. B. Robin, A. Theron, P. Quittet, C. Exbrayat, J. B. Gaillard in Annals of Hematology (2022)

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    Article

    Low doses of GM-CSF (molgramostim) and G-CSF (filgrastim) after cyclophosphamide (4 g/m2) enhance the peripheral blood progenitor cell harvest: results of two randomized studies including 120 patients

    The use of a combination of G-CSF and GM-CSF versus G-CSF alone, after cyclophosphamide (4 g/m2) was compared in two randomized phase III studies, including 120 patients. In study A, 60 patients received 5 × 2 μg...

    P Quittet, P Ceballos, E Lopez, Z Y Lu, P Latry, C Becht in Bone Marrow Transplantation (2006)

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    Article

    Optimizing the use of anti-interleukin-6 monoclonal antibody with dexamethasone and 140 mg/m2 of melphalan in multiple myeloma: results of a pilot study including biological aspects

    Interleukin-6 (IL-6) is a major survival factor for multiple myeloma (MM) cells preventing apoptosis induced by dexamethasone (DEX) or chemotherapy. In all, 24 consecutive patients with MM in first-line therap...

    J-F Rossi, N Fegueux, Z Y Lu, E Legouffe, C Exbrayat in Bone Marrow Transplantation (2005)

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    Article

    Enhanced graft-versus-tumor effect following dose-reduced conditioning and allogeneic transplantation for refractory lymphoid malignancies after high-dose therapy

    Non-myeloablative regimens have been proven to allow engraftment following allogeneic stem cells transplantation (allo-SCT) with minimal procedure-related toxicity. Conventional allo-SCT may produce remissions...

    M Mohty, N Fegueux, C Exbrayat, ZY Lu, E Legouffe, P Quittet in Bone Marrow Transplantation (2001)