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Article
Discontinuation of tyrosine kinase inhibitor in chronic myeloid leukemia: a retrospective cohort in east occitania
Tyrosine kinase inhibitor (TKI) discontinuation in chronic phase chronic myeloid leukemia (CML) patients has been examined in a real-life setting in the east occitania region of France. We have collected sex, ...
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Chapter and Conference Paper
Analyse des cancers de l’intervalle du sein dans les départements français disposant d’un registre des cancers
Depuis 2008, des travaux sur les cancers de l’intervalle sont réalisés régulièrement pour suivre les évolutions de la performance du programme de dépistage des cancers en France. La sensibilité de ce programme...
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Chapter and Conference Paper
Estimation du surdiagnostic lié au dépistage du cancer du sein par mammographie : étude en population générale
Le dépistage du cancer du sein par mammographie entraîne une diminution de la mortalité par cancer du sein mais peut présenter certains effets indésirables comme l’inconfort de la mammographie, la présence de ...
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Article
Association of diagnostic work-up with subsequent attendance in a breast cancer screening program for false-positive cases
The objective of this study is to determine whether the likelihood of returning for routine breast cancer screening differed for false-positive cases depending on the diagnostic work-up. Using the original dat...
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Article
Low doses of GM-CSF (molgramostim) and G-CSF (filgrastim) after cyclophosphamide (4 g/m2) enhance the peripheral blood progenitor cell harvest: results of two randomized studies including 120 patients
The use of a combination of G-CSF and GM-CSF versus G-CSF alone, after cyclophosphamide (4 g/m2) was compared in two randomized phase III studies, including 120 patients. In study A, 60 patients received 5 × 2 μg...
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Article
Optimizing the use of anti-interleukin-6 monoclonal antibody with dexamethasone and 140 mg/m2 of melphalan in multiple myeloma: results of a pilot study including biological aspects
Interleukin-6 (IL-6) is a major survival factor for multiple myeloma (MM) cells preventing apoptosis induced by dexamethasone (DEX) or chemotherapy. In all, 24 consecutive patients with MM in first-line therap...
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Article
Enhanced graft-versus-tumor effect following dose-reduced conditioning and allogeneic transplantation for refractory lymphoid malignancies after high-dose therapy
Non-myeloablative regimens have been proven to allow engraftment following allogeneic stem cells transplantation (allo-SCT) with minimal procedure-related toxicity. Conventional allo-SCT may produce remissions...