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Article
Histone deacetylase inhibitors interrupt HSP90•RASGRP1 and HSP90•CRAF interactions to upregulate BIM and circumvent drug resistance in lymphoma cells
Histone deacetylase (HDAC) inhibitors, which are approved for the treatment of cutaneous T-cell lymphoma and multiple myeloma, are undergoing evaluation in other lymphoid neoplasms. How they kill susceptible c...
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Article
Open AccessP8.4 Non-Invasive Assessment of Local Pulse Wave Velocity Using Electromechanical Sensors: Feasibility Study in a Healthy Population
The assessment of local hemodynamics, namely in the carotid artery, has recently gained clinical relevance due to its significance in the development of coronary and cerebrovascular diseases. Local pulse wave ...
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Article
Open AccessP2.11 Assessment of Carotid Distention Waveform and Local Pulse Wave Velocity Determination by a Novel Optical System
Measurement of structural and functional properties of the arterial tree produce important clinical indexes for the assessment of cardiovascular risk, vascular adaptation, and therapeutic efficacy. An optical ...
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Article
Study of the effects of foliar application of ABA during acclimatization
This study aims to elucidate the effects of abscisic acid (ABA) foliar application on plant hardening during ex vitro acclimatization using a forest model species Ulmus minor L. Plant leaves were sprayed with ABA...
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Chapter and Conference Paper
Assessment of the Pulse Wave Variability for a New Non-invasive Device
The main motivation of this work was to provide a valid contribution for the assessment of the cardiovascular condition by the analysis of several Arterial Pressure Waveform (APW) parameters collected by a new...
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Chapter and Conference Paper
Clinical Test for Validation of a New Optical Probe for Hemodynamic Parameters Assessment
The assessment of the cardiovascular system condition based on multiple parameters allows a more precise and accurate diagnosis of the heart and arterial tree condition. For this reason, the interest in non-in...
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Chapter and Conference Paper
Characterization of an Acoustic Based Device for Local Arterial Stiffness Assessment
Arterial stiffness, recognized as an independent predictor of cardiovascular events, can be assessed non-invasively by regional and local methods. The present work proposes and describes a novel and low-cost d...
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Chapter and Conference Paper
Non-contact Pulse Wave Velocity Assessment Using Optical Methods
The clinical relevance of pulse wave velocity (PWV), as an indicator of cardiac risk associated to arterial stiffness, has gained clinical relevance over the last years. Optic sensors are an attractive instrum...
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Article
Open AccessP1.21 Arterial Distensibility in Young Individuals – Comparison of Arterial Distensibility Through the Measurement of Pulse Wave Velocity in Young Sportsmen Versus Non-Sportsmen
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Article
Open AccessEffects of low and high tidal volume and pentoxifylline on intestinal blood flow and leukocyte-endothelial interactions in mechanically ventilated rats
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Article
A Raman laser intensity sensor induced by the cooperative Rayleigh scattering in a ring configuration
In this work, a laser sensor is described that uses the multipath interference produced inside a ring cavity to measure the power loss induced by a moving taper intensity sensor. The laser is created due to th...
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Chapter and Conference Paper
Optically Isolated Current Source
This work addresses two different issues associated with the design voltage controlled current sources (VCSS): galvanic isolation between the load and the control voltage and loss of performance due to operati...
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Chapter and Conference Paper
Programmable Test Bench for Hemodynamic Studies
The non-invasive assessment of hemodynamic parameters has been a permanent challenge posed to the scientific community. The literature shows many contributions to this quest expressed as algorithms dedicated t...
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Chapter and Conference Paper
Slit-lamp Based Ocular Fluorometry Scanning
The aim of this work is to develop and present new slit-lamp based instrumentation and methods to measure anterior segment ocular fluorescence with clinical significance, mainly in diabetic patients. With thos...
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Article
Gas exchange and water relations of three Vitis vinifera L. cultivars growing under Mediterranean climate
Optical characteristics, contents of photosynthetic pigments, total soluble sugars, and starch, rates of gas exchange, chlorophyll (Chl) a fluorescence, and leaf water relations were analysed in three Vitis vinif...
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Article
SEPT2 is a new fusion partner of MLL in acute myeloid leukemia with t(2;11)(q37;q23)
We have identified a new mixed lineage leukemia (MLL) gene fusion partner in a patient with treatment-related acute myeloid leukemia (AML) presenting a t(2;11)(q37;q23) as the only cytogenetic abnormality. Fluore...
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Article
Intestinal blood flow and pCO2 gradients in arterial and venous mesenteric blood flow obstruction
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Article
Frequency of NUP98-NSD1 fusion transcript in childhood acute myeloid leukaemia