32 Result(s)

Article

Multiplexed targeted sequencing of recurrent fusion genes in acute leukaemia

P Ruminy, V Marchand, N Buchbinder, T Larson, B Joly, D Penther, E Lemasle… in Leukemia (2016)

Article

High rate of TNFRSF14 gene alterations related to 1p36 region in de novo follicular lymphoma and impact on prognosis

E Launay, C Pangault, P Bertrand, F Jardin, T Lamy, H Tilly, K Tarte, C Bastard… in Leukemia (2012)

Article

The isotype of the BCR as a surrogate for the GCB and ABC molecular subtypes in diffuse large B-cell lymphoma

Gene expression profiling has identified two major molecular subtypes of diffuse large B-cell lymphoma (DLBCL) that are histologically indistinguishable but differ in cure rates. Here, we investigated whether ...

P Ruminy, P Etancelin, L Couronné, F Parmentier, V Rainville, S Mareschal… in Leukemia (2011)

Article

Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33)

I Nagel, S Bug, H Tönnies, O Ammerpohl, J Richter, I Vater, E Callet-Bauchu… in Leukemia (2009)

Article

Recurrent genomic aberrations combined with deletions of various tumour suppressor genes may deregulate the G1/S transition in CD4+CD56+ haematodermic neoplasms and contribute to the aggressiveness of the disease

CD4+CD56+ haematodermic neoplasms (HDN) constitute a rare disease characterized by aggressive clinical behaviour and a poor prognosis. Tumour cells from HDN are leukaemic counterparts of plasmacytoid dendritic...

F Jardin, M Callanan, D Penther, P Ruminy, X Troussard, J P Kerckaert, M Figeac… in Leukemia (2009)

Article

Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases

The t(8;16)(p11;p13) is a rare translocation involved in de novo and therapy-related myelomonocytic and monocytic acute leukemia. It fuses two genes encoding histone acetyltransferases (HATs), MYST3 located at 8p...

A Murati, C Gervais, N Carbuccia, P Finetti, N Cervera, J Adélaïde, S Struski… in Leukemia (2009)

Article

The most frequent t(14;19)(q32;q13)-positive B-cell malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia

E Chapiro, I Radford-Weiss, C Bastard, I Luquet, C Lefebvre, E Callet-Bauchu… in Leukemia (2008)

Article

The expression of 16 genes related to the cell of origin and immune response predicts survival in elderly patients with diffuse large B-cell lymphoma treated with CHOP and rituximab

Gene expression profiles have been associated with clinical outcome in patients with diffuse large B-cell lymphoma (DLBCL) treated with anthracycline-containing chemotherapy. Using Affymetrix HU133A microarray...

J-P Jais, C Haioun, T J Molina, D S Rickman, A de Reynies, F Berger… in Leukemia (2008)

Article

Acute myeloid leukaemia with 8p11 (MYST3) rearrangement: an integrated cytologic, cytogenetic and molecular study by the groupe francophone de cytogénétique hématologique

Thirty cases of acute myeloid leukaemia (AML) with MYST histone acetyltransferase 3 (MYST3) rearrangement were collected in a retrospective study from 14 centres in France and Belgium. The mean age at diagnosis w...

C Gervais, A Murati, C Helias, S Struski, A Eischen, E Lippert, I Tigaud… in Leukemia (2008)

Article

Characterization of three t(3;8)(q27;q24) translocations from diffuse large B-cell lymphomas

P Bertrand, C Maingonnat, J M Picquenot, N Dastugue, D Penther, L Ysebaert… in Leukemia (2008)

Article

Conventional cytogenetics of nodular lymphocyte-predominant Hodgkin's lymphoma

A Stamatoullas, J-M Picquenot, C Dumesnil, P Ruminy, D Penther, P Bertrand… in Leukemia (2007)

Article

Comparison of a quantitative PCR method with FISH for the assessment of the four aneuploidies commonly evaluated in CLL patients

Four chromosomal defects associated with outcome are commonly evaluated by fluorescent in situ hybridization (FISH) in chronic lymphocytic leukemia (CLL), namely deletions of the 13q13-q14, 11q22 and 17p13 region...

C Bastard, G Raux, C Fruchart, F Parmentier, D Vaur, D Penther, X Troussard… in Leukemia (2007)

Article

Map** of MYC breakpoints in 8q24 rearrangements involving non-immunoglobulin partners in B-cell lymphomas

Chromosomal translocations joining the immunoglobulin (IG) and MYC genes have been extensively reported in Burkitt's and non-Burkitt's lymphomas but data concerning MYC rearrangements with non-IG partners are sca...

P Bertrand, C Bastard, C Maingonnat, F Jardin, C Maisonneuve, M-N Courel… in Leukemia (2007)

Article

Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936

Polymerase chain reaction (PCR) assessment of clonal T-cell receptor (TCR) and immunoglobulin (Ig) gene rearrangements is an important diagnostic tool in mature T-cell neoplasms. However, lack of standardized ...

M Brüggemann, H White, P Gaulard, R Garcia-Sanz, P Gameiro, S Oeschger… in Leukemia (2007)

Article

Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets. Report of the BIOMED-2 Concerted Action BHM4-CT98-3936

Polymerase chain reaction (PCR) assessment of clonal immunoglobulin (Ig) and T-cell receptor (TCR) gene rearrangements is an important diagnostic tool in mature B-cell neoplasms. However, lack of standardized ...

P A S Evans, Ch Pott, P J T A Groenen, G Salles, F Davi, F Berger, J F Garcia… in Leukemia (2007)

Article

Prospective multicentric molecular study for poor prognosis fusion transcripts at diagnosis in adult B-lineage ALL patients: the LALA 94 experience

C Picard, S Hayette, C Bilhou-Nabera, J M Cayuela, E Delabesse, N Frenoy… in Leukemia (2006)

Article

Allogeneic stem cell transplantation improves the outcome of adults with t(1;19)/E2A-PBX1 and t(4;11)/MLL-AF4 positive B-cell acute lymphoblastic leukemia: results of the prospective multicenter LALA-94 study

Adult patients with acute lymphoblastic leukemia (ALL) and t(1;19)/E2A-PBX1 or t(4;11)/MLL-AF4 have a poor outcome. We have evaluated the impact of an intensified post-remission therapy using a high-dose chemothe...

N Vey, X Thomas, C Picard, T Kovascovicz, C Charin, J M Cayuela, H Dombret… in Leukemia (2006)

Article

Novel Ig V gene features of t(14;18) and t(3;14) de novo diffuse large B-cell lymphoma displaying germinal center-B cell like and non-germinal center-B cell like markers

F Jardin, S S Sahota, P Ruminy, F Parmentier, J M Picquenot, V Rainville… in Leukemia (2006)