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  1. Article

    Open Access

    Impaired p65 degradation by decreased chaperone-mediated autophagy activity facilitates epithelial-to-mesenchymal transition

    Aberrant activation of nuclear factor-κB (NF-κB) has been observed in a wide range of human cancers and is thought to promote tumorigenesis and metastasis. As a central component of NF-κB pathway, p65 protein ...

    J Tang, M-N Zhan, Q-Q Yin, C-X Zhou, C-L Wang, L-L Wo, M He, G-Q Chen… in Oncogenesis (2017)

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  2. Article

    HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation

    Hypoxia-inducible factor 1 (HIF-1) is a crucial transcription factor for the cellular adaptive response to hypoxia, which contributes to multiple events in cancer biology. MicroRNAs (miRNAs) are involved in al...

    M He, Q-Y Wang, Q-Q Yin, J Tang, Y Lu, C-X Zhou, C-W Duan… in Cell Death & Differentiation (2013)

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  3. No Access

    Article

    The downregulation of onzin expression by PKCɛ-ERK2 signaling and its potential role in AML cell differentiation

    Onzin is a small, novel, and highly conserved protein with unique structure and tissue-restricted expression. The regulation of its expression and biological roles remain greatly elusive. Here, we provide the ...

    S-F Wu, Y Huang, J-K Hou, T-T Yuan, C-X Zhou, J Zhang, G-Q Chen in Leukemia (2010)

  4. Article

    Erratum: Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells

    Correction to: Oncogene (2006) 25: 6618–6627. doi:10.1038/sj.onc.1209677 Due to a typesetting error, on page 6618 Dr T Wiedmer's name was omitted from the list of authors. Dr Wiedmer is affiliated with the Dep...

    Y Huang, Q Zhao, C-X Zhou, Z-M Gu, D Li, H-Z Xu, T Wiedmer, P J Sims, K-W Zhao… in Oncogene (2006)

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  5. No Access

    Article

    Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells

    Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated protein which is localized in either the cell membrane or nucleus depending on its palmitoylated state. The increasing evidence showed the biologi...

    Y Huang, Q Zhao, C-X Zhou, Z-M Gu, D Li, H-Z Xu, P J Sims, K-W Zhao, G-Q Chen in Oncogene (2006)