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Article
The maternal cytoplasmic environment may be involved in the viability selection of gametes and zygotes
Segregation distortion is the phenomenon whereby the observed genotypic frequencies of a locus fall outside the expected Mendelian segregation ratio, and it is increasingly recognised as a potentially powerful...
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Article
Dual-wavelength passively mode-locked Nd: GdVO4 laser with orthogonal polarizations
A passively mode-locked dual-wavelength Nd: GdVO4 laser with orthogonal polarizations is experimentally demonstrated. By changing the absorbed pump power, the laser can mode lock either at 1063 nm (with π polariz...
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Article
Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc
Thanatos-associated proteins (THAPs) are zinc-dependent, sequence-specific DNA-binding factors involved in cell proliferation, apoptosis, cell cycle, chromatin modification and transcriptional regulation. THAP...
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Article
Overexpression of a hematopoietic transcriptional regulator EDAG induces myelopoiesis and suppresses lymphopoiesis in transgenic mice
Erythroid differentiation-associated gene (EDAG) is a hematopoietic tissue-specific gene that is highly expressed in the earliest CD34+ lin− bone marrow (BM) cells and involved in the proliferation and differenti...
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Article
Open AccessFamilial aggregation of lung cancer in a high incidence area in China
To investigate whether lung cancer clusters in families in a high incidence county of China, an analysis was conducted using data on domestic fuel history and tobacco use for family members of 740 deceased lun...
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Article
EDAG regulates the proliferation and differentiation of hematopoietic cells and resists cell apoptosis through the activation of nuclear factor-κB
Erythroid differentiation-associated gene (EDAG) is considered to be a human hematopoiesis-specific gene. Here, we reported that downregulation of EDAG protein in K562 cells resulted in inhibition of growth an...