-
Article
Open AccessAssociation between impaired fasting glycaemia in pediatric obesity and type 2 diabetes in young adulthood
In adults, impaired fasting glycemia (IFG) increases the risk for type 2 diabetes mellitus (T2DM). This study aimed to investigate to which extent children with obesity develop T2DM during early adulthood, and...
-
Article
Open AccessRisk of symptomatic gallstones and cholecystectomy after a very-low-calorie diet or low-calorie diet in a commercial weight loss program: 1-year matched cohort study
Concern exists regarding gallstones as an adverse event of very-low-calorie diets (VLCDs; <800 kcal per day).
-
Article
Open AccessImpaired fasting glucose prevalence in two nationwide cohorts of obese children and adolescents
Impaired fasting glucose (IFG), a pre-stage to type 2 diabetes in adults, is also present in obese children. A large variation of the occurrence has been recorded, but the true prevalence is unknown due to lac...
-
Article
Thyroid autoimmunity in relation to islet autoantibodies and HLA-DQ genotype in newly diagnosed type 1 diabetes in children and adolescents
The aim of this work was to investigate, in children newly diagnosed with type 1 diabetes: (1) the prevalence of autoantibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TGAb); and (2) the associat...
-
Article
Open AccessDetermination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children
The Fat mass and obesity-associated gene (FTO) was the first gene reliably associated with body mass index in genome-wide association studies on a population level. At present, the genetic variations within the F...
-
Article
Age-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes
The major histocompatibility complex class II transactivator (CIITA) gene (16p13) has been reported to associate with susceptibility to multiple sclerosis, rheumatoid arthritis and myocardial infarction, recently...
-
Article
Two-year outcome of laparoscopic Roux-en-Y gastric bypass in adolescents with severe obesity: results from a Swedish Nationwide Study (AMOS)
The prevalence of obesity among adolescents has increased and we lack effective treatments.
-
Article
Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden
Type 1 diabetes and obesity has increased in childhood. We therefore tested the hypothesis that type 1 diabetes human leukocyte antigen DQ (HLA-DQ) risk genotypes may be associated with increased body mass ind...
-
Article
Open AccessGenetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children
Recently a genome-wide association analysis from five European populations identified a polymorphism located downstream of the mannosyl-(α-1,3)-glycoprotein-β-1,2-N-acetylglucosaminyltransferase (MGAT1) gene that...
-
Article
Open AccessAssociations between severity of obesity in childhood and adolescence, obesity onset and parental BMI: a longitudinal cohort study
To explore the relationship between severity of obesity at age 7 and age 15, age at onset of obesity, and parental body mass index (BMI) in obese children and adolescents.
-
Article
Association between nocturnal blood pressure dip** and insulin metabolism in obese adolescents
The purpose of this study was to analyze the relationship between insulin–glucose metabolism, nocturnal blood pressure (BP) dip** and cardiac left ventricular mass (LVM) in obese adolescents without diabetes.
-
Article
A 4-year, cluster-randomized, controlled childhood obesity prevention study: STOPP
To assess the efficacy of a school-based intervention programme to reduce the prevalence of overweight in 6 to 10-year-old children.
-
Article
Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents
The global prevalence of obesity and overweight is increasing rapidly among adults as well as among children and adolescents. Recent genome-wide association studies have provided strong support for association...
-
Article
Effect of fasting on young adults who have symptoms of hypoglycemia in the absence of frequent meals
Among otherwise healthy adults, there is a subgroup of individuals who develop symptoms of hypoglycemia during episodes of food restriction. The aim of the present study was to investigate whether such individ...
-
Article
Type 1 Diabetic Serum Interferes with Pancreatic β-cell Ca2+ -Handling
The aim of this study was to clarify the frequency of patients with type 1 diabetes that have serum that increases pancreatic β-cell cytoplasmic free Ca2+ concentration, [Ca2+]i, and if such an effect is also pre...
-
Article
Interventions to prevent obesity in children and adolescents: a systematic literature review
Preventive measures to contain the epidemic of obesity have become a major focus of attention. This report reviews the scientific evidence for medical interventions aimed at preventing obesity during childhood...
-
Article
Eating disorder traits in obese children and adolescents
The aim of the present study was to investigate the prevalence of eating disorder (ED) traits among obese children and adolescents. The Swedish version of the Eating Disorder Inventory for Children, consisting...
-
Article
Weak Evidence of Thyrotropin Receptors in Primary Cultures of Human Osteoblast-like Cells
Extra-thyroidal thyrotropin (TSH) receptors (TSHRs) have been demonstrated in several tissues and cells, including human and rat osteosarcoma cell lines. We have explored whether human TSHR (hTSHRs) also are p...
-
Article
Measurement of visceral adipose tissue by DXA combined with anthropometry in obese humans
OBJECTIVE: To get accurate measurements of visceral adipose tissue (VAT) using dual energy X-ray absorptiometry (DXA).
-
Article
Synthesis, integration, and electrical properties of individual single-walled carbon nanotubes
High-quality single-walled carbon nanotubes (SWNTs) are synthesized by chemical vapor deposition (CVD) of methane on silicon-dioxide substrates at controlled locations using patterned catalytic islands. With t...
