6 Result(s)
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Article
Open AccessAssociation between impaired fasting glycaemia in pediatric obesity and type 2 diabetes in young adulthood
In adults, impaired fasting glycemia (IFG) increases the risk for type 2 diabetes mellitus (T2DM). This study aimed to investigate to which extent children with obesity develop T2DM during early adulthood, and...
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Article
Open AccessRisk of symptomatic gallstones and cholecystectomy after a very-low-calorie diet or low-calorie diet in a commercial weight loss program: 1-year matched cohort study
Concern exists regarding gallstones as an adverse event of very-low-calorie diets (VLCDs; <800 kcal per day).
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Article
Open AccessImpaired fasting glucose prevalence in two nationwide cohorts of obese children and adolescents
Impaired fasting glucose (IFG), a pre-stage to type 2 diabetes in adults, is also present in obese children. A large variation of the occurrence has been recorded, but the true prevalence is unknown due to lac...
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Article
Open AccessDetermination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children
The Fat mass and obesity-associated gene (FTO) was the first gene reliably associated with body mass index in genome-wide association studies on a population level. At present, the genetic variations within the F...
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Article
Open AccessGenetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children
Recently a genome-wide association analysis from five European populations identified a polymorphism located downstream of the mannosyl-(α-1,3)-glycoprotein-β-1,2-N-acetylglucosaminyltransferase (MGAT1) gene that...
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Article
Open AccessAssociations between severity of obesity in childhood and adolescence, obesity onset and parental BMI: a longitudinal cohort study
To explore the relationship between severity of obesity at age 7 and age 15, age at onset of obesity, and parental body mass index (BMI) in obese children and adolescents.
