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Open AccessMicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes
Recent advances in cancer biology have emerged important roles for microRNAs (miRNAs) in regulating tumor responses. However, their function in mediating intercellular communication within the tumor microenvir...
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Open AccessStrong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs
Increasing the efficacy of targeted cancer therapies requires the identification of robust biomarkers suitable for patient stratification. This study focused on the identification of molecular mechanisms causi...
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Measurement and Simulation of Combustion Noise emitted from Swirl Burners
A major uncertaincy, when designing combustors is the influence of geometrical patterns of the design on the combustion noise generated. In order to determine the mechanisms and processes that influence the no...
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Living with death: the evolution of the mitochondrial pathway of apoptosis in animals
The mitochondrial pathway of cell death, in which apoptosis proceeds following mitochondrial outer membrane permeabilization, release of cytochrome c, and APAF-1 apoptosome-mediated caspase activation, represents...
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Prediction of Pressure Oscillations in a Premixed Swirl Combustor Flow and Comparison to Measurements
The most common and reliable technique used for flame stabilization of industrial combustors with high thermal loads is the application of strongly swirling flows. In addition to stabilization, swirl flames of...
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Biosynthesis of coronatine, a thermoregulated phytotoxin produced by the phytopathogen Pseudomonas syringae
Coronatine (COR) is a non-host-specific phytotoxin that is produced by several different pathovars in the species Pseudomonas syringae. COR consists of two distinct components: coronafacic acid (CFA), which is s...
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Consolidation of Vineyards, Mitigations, and Survival of the Common Wall Lizard (Podarcis Muralis) in Isolated Habitat Fragments
Old vineyards with well structured walls and diverse habitat elements on steep south facing slopes are an important component of the cultural heritage along the river valleys of south-west Germany. Such vineya...
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Methylmalonic acidaemia: haplotype analysis of the methylmalonyl-CoA-mutase gene in Europe
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Haplotype analysis and a newMspl-polymorphism at the phenylalanine hydroxylase gene in the Arabian population
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Ueber die Brechungsexponenten von Salzlösungen
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Einen Apparat zum Aufsammeln von Gasen
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